Effects of Interrupting Prolonged Sitting With Different Standing Intervals on Vascular Health in Women
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Blood Pressure
研究概览
简要总结
The goal of this clinical trial is to examine the effects of interrupting prolonged sitting with different standing intervals on vascular health in healthy women aged 18-45 years. The main questions it aims to answer are:
Does interrupting prolonged sitting with short standing intervals (10 minutes every hour) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)? Does interrupting prolonged sitting with prolonged intermittent standing intervals (30 minutes every hour divided into three 10-minute standing bouts) improve blood pressure and pulse wave velocity more than prolonged continuous standing intervals (30 minutes every hour)?
The researcher will compare three different sitting interruption conditions to evaluate their effects on vascular health outcomes:
Standing for 10 minutes every hour. Continuous standing for 30 minutes every hour. Intermittent standing for 30 minutes every hour divided into three 10-minute standing bouts.
Participants will:
Attend three experimental sessions in random order separated by at least 7 days.
Complete 3 hours of sitting with different standing interruption protocols. Undergo measurements of blood pressure, pulse wave velocity, and heart rate before sitting and after each hour of the experiment.
Undergo height, weight, and body mass index measurements.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Female participants aged 18-45 years. Healthy individuals with normal blood pressure levels (systolic blood pressure <130 mmHg and diastolic blood pressure <80 mmHg).
- •Body mass index (BMI) less than 30 kg/m². Ability to stand without support. No history of cardiovascular disease or chronic diseases that may affect study outcomes.
排除标准
- •Pregnancy or breastfeeding. Back injuries preventing prolonged sitting. Use of medications that may affect cardiovascular responses, including antihypertensive, antidiabetic, antidepressant, or hormonal medications.
- •Presence of chronic diseases or cardiovascular conditions affecting vascular health.
研究组 & 干预措施
Short Standing Interval
Participants will complete 3 hours of sitting interrupted with 10 minutes of standing every hour.
干预措施: Short Standing Interval (Behavioral)
Continuous Standing Interval
Participants will complete 3 hours of sitting interrupted with 30 continuous minutes of standing every hour.
干预措施: Continuous Standing Interval (Behavioral)
Intermittent Standing Interval
Participants will complete 3 hours of sitting interrupted with 30 minutes of standing every hour divided into three 10-minute standing bouts.
干预措施: Intermittent Standing Interval (Behavioral)
结局指标
主要结局
Blood Pressure
时间窗: Baseline, 1 hour, 2 hours, and 3 hours
Systolic and diastolic blood pressure will be measured before sitting and after each hour during the experimental sessions.
Pulse Wave Velocity
时间窗: Baseline, 1 hour, 2 hours, and 3 hours
Heart Rate
时间窗: Baseline, 1 hour, 2 hours, and 3 hours
次要结局
未报告次要终点
研究者
Bushra Khalid Alharbi
Physical Education Teacher and Master's Student
King Saud University