Observational Study of EEG Monitoring of Patients in the Emergency Department
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Electroencephalogram (EEG)
研究概览
简要总结
This study seeks to investigate whether drug effects in suspected overdose patients could be identified using the electroencephalogram (EEG). From previous work it is known that different classes of anesthetic drugs have specific "EEG signatures" related to the drug mechanisms. Many of the drugs of abuse that are frequently encountered in overdose patients are similar or identical to anesthetic drugs. The hypothesis for this study is that the EEG could be used to characterize the brain effects of intoxicants using EEG in the ED setting. Such monitoring could one day help clinicians and first responders at the point-of-care make more informed decisions to improve the care of overdose patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients aged 18 years and older who present to the ED with suspected use of a potential drug of abuse
排除标准
- •Hemodynamic instability or other acute medical condition for which the primary treating team does not thing it would be appropriate or safe for the study staff to approach the patient
- •The patient has an overt head trauma or deformity of the face which would preclude application of the forehead EEG monitoring lead
- •The patient has dermatological issues or skin conditions on the forehead
- •The patient has known dementia and/or mental impairment
- •The patient is a prisoner
- •The patient is an employee or student at one of the study sites.
结局指标
主要结局
Electroencephalogram (EEG)
时间窗: 24 hours
Subject EEG activity following arrival to Emergency Department with suspected overdose, including EEG waveform, spectrum, spectrogram, and power in the slow (0.1-1 Hz), delta (1 to 4 Hz), theta (4 to 8 Hz), alpha (8 to 12 Hz), beta (12 to 25 Hz), and gamma (25 to 70 Hz) bands.
次要结局
未报告次要终点
研究者
Patrick L. Purdon
Nathaniel M. Sims Endowed Chair in Anesthesia Innovation and Bioengineering
Massachusetts General Hospital