Long-term Evaluation of Patients with Fulguration of Posterior Urethral Valve: a Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 35
- 主要终点
- The rate of spontaneous voiding with insignificant or absent PMR ( according to equation to age ) after one year from fulguration of the PUV.
研究概览
简要总结
To evaluate the long-term outcome after fulguration of the posterior urethral valve.
详细描述
Posterior Urethral Valves (PUV) are the most common cause of lower urinary tract obstruction. More severe forms are detected early in pregnancy (mainly type I), while other forms are usually discovered later in childhood when investigating lower urinary tract symptoms. Bladder dysfunction is common and is associated with urinary incontinence in about 55% (0%-72%). Despite the removal of the obstruction by urethral valve ablation, pathological changes in the urinary tract can occur with progressive bladder dysfunction, which can cause deterioration of the upper urinary tract as well. For this reason, all children with PUV require long-term follow-up, always until puberty. In many cases, the life-long current status is uncertain. The current literature lacks research on long-term outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Patients with fulguration of PUV since 1 year or more
排除标准
- •Patients with neurogenic bladder or meningocele or spina bifida .
- •Patients with renal parenchymal disease and inflammation not related to posterior urethral valve .
- •Diabetic patients .
- •Parental refusal .
结局指标
主要结局
The rate of spontaneous voiding with insignificant or absent PMR ( according to equation to age ) after one year from fulguration of the PUV.
时间窗: One year postoperative
次要结局
未报告次要终点
研究者
keroles Ashraf Soliman
Principal Investigator
Assiut University
