NCT07001527已完成3 期
Dressing Impregnated With Chlorhexidine and Vancomycin for the Prophylaxis of Central Venous Catheter-related Infections - a Randomized Trial
Hospital Universitario Evangelico de Curitiba1 个研究点 分布在 1 个国家目标入组 516 人开始时间: 2022年6月1日最近更新:
适应症
干预措施
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 516
- 试验地点
- 1
- 主要终点
- Infection
研究概览
简要总结
You are being invited as a volunteer to participate in the study "Dressing impregnated with chlorhexidine and vancomycin for the prophylaxis of central venous catheter-related infections." The objective is to evaluate the incidence of bloodstream infection related to the catheter in ICU patients with central venous catheters (CVC), using dressings impregnated or not with chlorhexidine/vancomycin. We believe this study is important as it aims to evaluate a new dressing method intended to reduce bloodstream-related infections.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •IInclusion criteria included: age over 18 years, admitted to the ICU, need for a CVC placed in the ICU by the trained team, use of the CVC for a period exceeding 72 hours, and intact skin in the area of contact with the dressing. CVC inserted outside the ICU and need for two CVCs in the same patient simultaneously were
排除标准
- •. A subsequent CVC could not be randomized. Other infections were not excluded during the evaluation. Only short-term CVC were evaluated (long-term and hemodialysis were excluded).
研究组 & 干预措施
Control
Placebo Comparator
COmmon dressing
干预措施: Chlorhexidine (Device)
Impregnated
Active Comparator
Impregnated
干预措施: Chlorhexidine (Device)
结局指标
主要结局
Infection
时间窗: 30 days
CRBSI was the primary endpoint
次要结局
未报告次要终点
研究者
Felipe Francisco Bondan Tuon
Professor
Pontifícia Universidade Católica do Paraná
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Comparison of Chlorhexidine Impregnated Dressing and Standard DressingCatheter-Related InfectionsNCT04794231Istanbul Medeniyet University307
进行中（未招募）
不适用
The use of Cloth with antiseptic before surgery to prevent Surgical Site InfectioPreoperative PeriodHealth PromotionC01.539.947.692Surgical Wound InfectionE04.614.937N02.370RBR-8httxsEscola de Enfermagem da Universidade de São Paulo - EEUSP
已完成
2 期
Study of Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care UnitNosocomial InfectionsNCT00549393Johns Hopkins University5,659
已完成
不适用
STRIPES Study: Study To Reduce Infection Post cEsarean SectionChlorhexidine Gluconate ClothsEndometritisInfectious MorbiditySurgical Site InfectionsCesarean Section InfectionNCT02402907Icahn School of Medicine at Mount Sinai1,356
已完成
不适用
Eliminate Risk of Cardiac Surgical Site EventsSurgical Site InfectionsNCT01425697University of Rochester739