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临床试验/NCT06070155
NCT06070155招募中不适用

Effect of Aerobic Exercises on Some Trace Elements and the Quality of Life in Post-menopausal Women After Radiotherapy

Cairo University2 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2023年10月最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
28
试验地点
2
主要终点
trace elements levels

研究概览

简要总结

This study will be conducted on 28 participants who are survivors of breast cancer and underwent radiotherapy. The purpose of the current study is to investigate the effect of aerobic exercises on quality of life and serum levels of Zinc, Copper and iron in post-menopausal women who received radiotherapy after surviving breast cancer.

详细描述

Breast cancer (BC) is the most common type of cancer in women globally. Several studies observed changes in the serum blood levels of trace elements in BC. Essential trace elements have relevant functions in a large number of cellular processes, with multiple roles in the correct functioning of metabolic enzymes.

There were previous trials to investigate the effect of exercise on trace elements in different populations as in the elite sportsmen. Some other studies to investigate the effect of exercise on breast cancer survivors for instance (Duijts et al., 2011) stated that physical exercise has effects on psychosocial functioning and health-related quality of life in breast cancer patients and survivors. Also, (Lambrigts et al., 2022) stated that aerobic exercise is the possible easiest solution to improve quality of life. Lastly, (Lipsett et al., 2017) proved that exercise during adjuvant radiotherapy for breast cancer has positive impact on reducing fatigue and improve quality of life . However, there are no previous studies to investigate the effect of exercise on trace elements in BC patients nor identifying the optimal dose or parameters of the exercise. So, this study is an attempt to add to the clinical knowledge in this field as it will be the first one that investigates the effect of aerobic exercise on trace elements in women survived BC.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

年龄范围
50 Years 至 60 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • All postmenopausal women with breast cancer and received radiotherapy immediately at the end of radiotherapy or max six months to one year in each group. after clinically diagnosed by Oncologist with breast cancer Stage I and II .
  • Their ages will range from 50-60 years old.
  • Good general Health (ECOG performance status 0-1).
  • Voluntary acceptance of participation in the study.

排除标准

  • Systematic chronic diseases (respiratory diseases, cardiovascular diseases...etc)
  • Cognitive dysfunction as well as neuromuscular or musculoskeletal impairment or disease affecting postural control or motion pattern.
  • Professional athletes.

结局指标

主要结局

trace elements levels

时间窗: 2 months

blood testing

次要结局

  • EORTC QLQ-C30(2 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Tarek Hussein Mostafa

Principal investigator

Cairo University

研究点 (2)

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