Model-Driven Paediatric European Digital Repository (MD-Paedigree) - MD-Paedigree

Vrije Universiteit Medisch Centrum0 个研究点目标入组 30 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•- Aged between 6 and 15 years (8-15 for the extended measurements for CP children)
•- Parent/guardian consent
•- Sufficient cognitive skills: able to follow simple instructions;For patient group only:
•- Children with a diagnosis of Cerebral Palsy following the definition of Rosenbaum: *Cerebral Palsy (CP) describes a group of permanent disorders of the development of movement and posture, causing activity limitation, that are attributed to non progressive disturbances that occurred in the developing foetal or infant brain. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, perception, cognition, communication, and behaviour, by epilepsy, and by secondary musculoskeletal problems*
•- GMFCS level I-II. (gross motor function classification system)
•- Spastic cerebral palsy

•- Patient history of functional surgery on bones and/or muscles of the legs; selective dorsal rhizotomy (not during follow up for the standard usual care group)
•- Lower limbs BoNT A injection in the last 6 months (not during follow up for the standard usual care group)
•- Patient history of hip, backbone and/or lower limb fracture;
•- Relevant visual deficit;
•- Behavioural problems of an extent that they can impede normal subject cooperation
•- Significant comorbidities
•- Claustrophobia.
•- A pacemaker or other non-removable metal-containing devices or objects
•- Not able to lie still for 3 times 7 minutes
•- Not willing to hear about *incidental findings*, potential unforeseen, clinically relevant abnormalities found in the MRI images.

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