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临床试验/CTRI/2024/02/062936
CTRI/2024/02/062936尚未招募不适用

Assessment of Prakriti in Sandhigat vata w.s.r. to preventive concept– A cross sectional study.

Ch brahm prakash ayurveda charak Sansthan1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年3月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
To assess prakriti in patient of sandhigata vata (osteoarthritis) by using WOMAC SCALE of 100 sample size.

研究概览

简要总结

Introduction-

Prakriti is one of the most important concepts and it is decided at the time of conception.

Whichever dosha predominantes at the time of union of sukra and sonita, the doshika constitution

is determined accordingly.1

It is an expression of body functions, in the form of morphology,

physiology, behaviour of an individual. Prakriti indicates toward phenotypic and genotypic

constitution.2Prakriti is of seven types, i.e., three according to each dosha, Vataj, Pittaj, Kaphaj,

three according to the combination of two doshas (Dwandwaj) and one due to all the three doshas

together (Samadoshaj). Among these, samadoshaj is considered as an excellent one because of

homeostatic state of dosha, each prakriti has specific physical and mental characteristics which

totally depend on the involvement of dosha.3 Prakriti means a normal or naturals state and there

should not be any dominance of doshas in the bodies of individuals. So such individuals as are

having the dominance of one or the other of the doshas cannot be described to have the normal

states of their body.4 Thus to use the correct term, they are vatal (having the dominance of vata),

pittala (having dominance of pitta) , slesmla (having dominance of kapha).Vatala, pittala, and

slesmala types of individuals are susceptible to vatika, paittika and slaismika diseases respectively

and such diseases in the respective types of individuals become very severe.5

In ayurveda all arthritic diseases are included in relation with asthi dhatu pradoshaj vikaraj

according to ayurveda we can correlate osteoarthritis with it as sandhigat vata osteoarthritis is by

far the most common form of arthritis .it is strongly associated with ageing and is a major cause

of pain and disability in older people. Pathologically ,it may be defined as a condition of synovial

joints characterized by focal loss of articular hyaline cartilage with proliferation of new. bone and

remodel ing of joint contour inflammation is not a prominent clinical feature. OA and

preferentially targets certain small and large joints but it Is not a disease or a single condition it

is best viewed as the dynamic repair process of synovial joints that may be triggered by a variety

of insults ,some but not all of which result in symptomatic joint failure. There are actually two

types of osteoarthritis; primary and secondary .These two forms of OA have the same symptoms

but, different causes .both primary and secondary OA involve the breakdown of cartilage in . joints

,which causes bones to rub together .osteoarthritis is the second most common rheumatologic

problem and it is the most frequent joint disease with a prevalence of 22%-39% in India OA is

more common in women than men .Nearly 45% of women over the age of 65 years have symptoms

while 70% of those over 65 years show radiological evidence of OA. This is because of the genetic predisposition of Indians towards knee arthritis, and a lifestyle that results in overuse of the knee

joints. The main challenges in treating joint replacements are the financial incapacity of patients

and deficient awareness among the people about health insurance. Among the chronic rheumatic

diseases hip and knee osteoarthritis is the most prevalent and is leading cause of pain and disability

in most countries world wide,its prevalence increases with age and generally affects women more

frequently than men. Determining region specific OA prevalence and risk factor profiles will

provide important information for planning future cost effective preventive strategies and health

care services.

Research question

Is there any association between Prakriti and osteoarthritis

Hypothesis

Null hypothesis

There is no co-relation between Prakriti and osteoarthritis

Alternative hypothesis

There is co-relation between Prakriti and osteoarthritis

Lacunae in existing knowledge

Not much fundamental research has been done with reference to Prakriti and osteoarthritis

Manifestation of osteoarthritis in different Prakriti has not been studied in much detail before.

Study on osteoarthritis its symptoms and prevalence rate has been done.

Previous work done: -

• Efficacy of leech therapy in the management of osteoarthritis.(RAI PK

AYU,2011)

• Clinical study of Agnikarma and pachatikta guggul in the management of

sandhivata (SHARMAAV AYU 2016)

• Clinical evaluation of Boswellia errata(shallaki)resin in the management of

sandhivata .GUPTA PK 2011

• Clinical evaluation of nirgundi taila in the management of sandhivata

DAS B Anc sci life 2003

Outcome of the study-

By this study after assessment of prakriti in sandhigat vata we can design lifestyle and

treatment protocols and preventive measures could be taken if prevalence of sandhigata

vata studied in different prakriti subjects

NEED OF THE STUDY: -

•Rise in environmental and genetic changes, which are implicated in the pathogenesis of

Sandhigata vata further indicates its increasing prevalence and incidence in coming future.

• By assessing the Prakriti of individuals suffering from sandhigata vata we can design lifestyle

and treatment protocol accordingly.

• By assessing Prakrit; disease outcome and severity can be predicted.

• Preventive measures could be taken if prevalence of sandhigata vata isstudied in different

constitution subjects.

Aim & objectives -

Aim-To assess Prakriti in sandhigata vata w.s.r to preventive concept.

Objectives –

• To determine sandhigata vata based on the diagnosis as mentioned in different

classical text and osteoarthritis diagnosis on the basis WOMAC score.

• Prakriti will be assessed by using a validated Dr. (Prof.) Kishor Patwardhan BHU

Prakriti Performa

• To determine the co-relation between Prakriti and osteoarthritis, .

Inclusion criteria:

  1. Diagnosed cases of osteoarthritis irrespective of gender and socio-economic status

  2. Age group 40- 60 years old.

  3. Subjects who can give their history and details for assessment on their own.

Exclusion criteria:

  1. Age below the 40 years and above the 60 years.

2.Subjects who cannot give their history and assessment details on their own.

3,Subjects who are bed –ridden.

4.Subjects suffering from carcinomatous or other infectious disorders.

研究设计

研究类型
Observational

入排标准

年龄范围
40.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Diagnosed cases of osteoarthritis irrespective of gender and socio-economic status
  • Age group 40- 60 years old.
  • Subjects who can give their history and details for assessment on their own.

排除标准

  • Age below the 40 years and above the 60 years.
  • 2.Subjects who cannot give their history and assessment details on their own.
  • 3,Subjects who are bed –ridden.
  • 4.Subjects suffering from carcinomatous or other infectious disorders.

结局指标

主要结局

To assess prakriti in patient of sandhigata vata (osteoarthritis) by using WOMAC SCALE of 100 sample size.

时间窗: 12 weeks

次要结局

  • It will help in determining daily regimen & dietary recommendations.(It will help in preventative care of sandigata vata / osteoporosis patients)

研究者

发起方
Ch brahm prakash ayurveda charak Sansthan
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr M.B.Gaur

CH. BRAHM PRAKASH AYURVED CHARAK SANSTHAN

研究点 (1)

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