jRCTs051180229招募中不适用
ALS biomarker research using patient clinical samples
未提供0 个研究点目标入组 49 人开始时间: 2019年4月19日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 49
- 主要终点
- Alteration of blood biomarkers
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomized Controlled Trial
- 干预模型
- Parallel Assignment
- 主要目的
- Basic Science
- 盲法
- Open(masking Not Used)
入排标准
- 年龄范围
- 20age old over 至 75age old under（—）
- 性别
- All
入选标准
- •Those who agree to attend the current clinical study among ALS patients joining an accompanying clinical trial "Phase 1/2 Dose Escalation Study of Bostinib in Patients with Amyotrophic Lateral Sclerosis (ALS)"
排除标准
- 未提供
结局指标
主要结局
Alteration of blood biomarkers
Alteration of blood biomarkers including SOD1, TDP-43, Src, c-Abl, etc.
Alteration of CSF biomarkers
Alteration of CSF biomarkers including neurofilament L, phosphorylated neurofilament H, SOD1, TDP-43, etc.
Alteration of urine biomarkers
Alteration of urine biomarkers including p75, etc.
Plasma concentration of bosutinib
Plasma concentration of bosutinib (through value)
CSF concentration of bosutinib
CSF concentration of bosutinib (through value)
Evaluation of biomarkers using iPS cells
Evaluation of biomarkers using iPS cells
次要结局
未报告次要终点
研究者
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