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临床试验/NCT06166368
NCT06166368已完成不适用

the Bispebjerg Study of Diurnal Variations

Bispebjerg Hospital0 个研究点目标入组 24 人开始时间: 2008年10月11日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
24
主要终点
hematology parameters

研究概览

简要总结

To evaluate the influence of time of day on the circulating concentrations of various biochemical markers in healthy men

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Medically healthy
  • Normal sleep-wake pattern

排除标准

  • acute or chronic medical diseases
  • had worked nightshifts the last 14 days before the study
  • transatlantic traveling the last 14 days before the study
  • had been smoking the last 14 days before the study
  • had an irregular sleep-wake pattern,
  • didn't sleep 7-8 hours pr night
  • were extreme morning- or evening types,
  • had plasma hemoglobin < 8.0 mmol/L
  • ody mass index (BMI) <18.5 kg/m2 or >24.9 kg/m2.

结局指标

主要结局

hematology parameters

时间窗: 24 hours

Composite measurement of hematological measurements

次要结局

  • Plasma levels of GIP(24 hours)
  • Plasma Levels of Glucagon(24 hours)
  • Plasma levels of GLP-1(24 hours)
  • Plasma levels of c-peptide(24 hours)
  • Plasma levels of glucose(24 hours)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Henriette P. Sennels

MD PhD.

Bispebjerg Hospital

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