NCT05718791招募中不适用
CXC-chemokine Ligand 9 (CXCL9) and Endothelial Activation and Stress Index (EASIX) for Prediction of Acute Graft Versus Host Disease
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- predictors of acute GVHD
研究概览
简要总结
The prediction of severe acute GVHD before it occurs is of high importance for ensuing clinical decisions and overall success of allogeneic SCT. The key immunologic signatures associated with clinical outcomes after different graft versus host disease prophylaxis methods or peripheral blood stem cell transplant are largely unknown.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients >18 year old admitted for allo SCT PB for malignant disease.
排除标准
- 未提供
结局指标
主要结局
predictors of acute GVHD
时间窗: CXCL9 combined with EASIX calculated at day 28 +/- 2 post SCT can be used as predictors of acute GVHD by day 100.
CXCL9 combined with EASIX can be used as predictors of acute GVHD
次要结局
未报告次要终点
研究者
Shatha Farhan
Clinical Assistant Professor
Henry Ford Health System
研究点 (1)
Loading locations...
相似试验
已完成
不适用
CEC Count Changes to Support GvHD Diagnosis.Graft vs Host DiseaseComplications of Organ Transplant Stem CellsEndothelial DysfunctionNCT02064972Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia50
Unknown
不适用
Biomarkers for Acute Graft-versus-host DiseaseAcute GVH DiseaseNCT02254798Assistance Publique - Hôpitaux de Paris315
招募中
不适用
The Role of Glycocalyx Integrity in the Primary Prevention of Major Cardiovascular EventsEndothelial DysfunctionArterial StiffnessNCT04646252University of Athens500
已完成
不适用
A retrospective observational study of risk factors for postoperative recurrence in early gastric cancerearly gastric cancerJPRN-UMIN000045382Wakayama Medical University1,001
招募中
不适用
Prediction of acute GVHD following hematopoietic stem cell transplantation by using MLR-ELISPOT assayJPRN-UMIN000009674Mie University Hospital25