CTRI/2023/12/060661尚未招募Unknown
A comparative study to evaluate the efficacy and safety of Vortioxetine and Escitalopram in patients with depression. - NI
Ronakkumar Chandubhai Patel0 个研究点目标入组 0 人开始时间: 待定最近更新:
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •All patients giving written consent will be taken.
- •Subjects >18 & <60 years of age of either gender, diagnosed to be suffering from depression as per ICD-10 (International classification of Diseases) with or without somatic symptoms or recurrent depressive disorder as per ICD- 10 with or without somatic symptoms, duration of current depressive episode is to be between 4 weeks to 12 months, and scoring =7 and = 34 on MADRS (Montgomery Asberg Depression Rating scale), 12 CGI-S (Clinical global impression) >2 and <6 on the initial visit will be enrolled in the study.
排除标准
- •Current or past comorbid diagnosis of schizophrenia, schizoaffective disorder, schizophreniform disorder, delusional disorder, a psychotic disorder not otherwise specified, mood-congruent or mood-incongruent psychotic features, bipolar disorder, alcohol or substance-use disorder, organic mental disorder including dementia, eating disorder, or obsessive compulsive disorder; presence of a seizure disorder; previous treatment with electroconvulsive therapy; currently pregnant/lactating women; and risk of suicide. • All patients with an unclear history of antidepressant treatment. Patients not giving informed consent. Patients scoring =6 on MADRS items number 10 (suicidal thoughts) at screening or baseline, history of non response to an adequate (6 week) trial of three or more antidepressant (with or without mood stabilizers) during the current episode, with imminent risk of suicide or injury to self, others, or property.
- •Besides, patients with current clinically significant neurological, metabolic (including typel diabetes), hepatic, renal, hematological, pulmonary. cardiovascular, gastrointestinal, and/or urological disorder such, as unstable angina, congestive heart failure (uncontrolled), or central nervous system (CNS) infection that would pose a risk to the subject if they were to participate in the study or that might confound the results of the study subjects with human immunodeficiency virus (HIV) seropositivity (or history of seropositivity), history of malignancy, or any chronic incapacitating illness will be excluded.
研究者
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