Effects of Menstrual Cycle-based Undulating Periodized Resistance Training in Women's Neuromuscular Abilities
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Maximal knee extensor strenght
研究概览
简要总结
The goal of this clinical trial is to assess the impact of menstrual cycle-based resistance training on neuromuscular function in female athletes.
The primary questions it aims to answer are :
- Does varying resistance training intensity according to menstrual phases improve maximal knee extensor strength?
- How do different training protocols affect voluntary activation, rate of force development, muscle stiffness, and vertical jump height?
Researchers will compare natural menstrual cycle groups with an oral contraceptive control group to determine if menstrual phase-specific training influences neuromuscular adaptations.
Participants will:
- Undergo 2 weekly resistance training sessions over 13 weeks with intensity adjustments based on menstrual phase
- Complete periodic neuromuscular assessments across three menstrual phases: early follicular, late follicular, and mid-luteal before and after resistance training intervention
详细描述
This study investigates the neuromuscular effects of menstrual cycle-based resistance training by comparing three distinct training protocols among female athletes with natural menstrual cycles and a control group of athletes using oral contraceptives. Hormonal fluctuations across the menstrual phases can impact muscle performance, recovery, and neuromuscular function. This trial aims to align training intensity with menstrual cycle phases to enhance neuromuscular adaptations.
Study Design and Population
The trial is a controlled, randomized, open-label design involving 60 recreationally active female athletes aged 18 and above. Participants are allocated into four groups:
N-PF: Natural menstrual cycle with increased training intensity during the follicular phase.
N-PL: Natural menstrual cycle with increased training intensity during the luteal phase.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Female athletes with natural menstrual cycles (eumenorrheic): Participants must have regular menstrual cycles lasting between 21 and 35 days, with at least 9 cycles per year.
- •Women using a low-dose monophasic estrogen-progestin oral contraceptive.
- •Age 18 or older: Participants must be legal adults.
- •Body Mass Index (BMI) between 18 and 30 kg/m².
- •No medical contraindications to high-level physical training or exercise.
- •Physically active: Engages in at least 3 hours of physical activity per week.
- •Informed consent: Provides written, informed consent to participate in the study.
- •Affiliation with a social security system (if applicable by local regulations).
排除标准
- 未提供
研究组 & 干预措施
N-PF (Natural Cycle - Follicular Phase-Intensified Training)
Female athletes with natural menstrual cycles who follow a resistance training program with increased intensity during the follicular phase and reduced intensity during the luteal phase. This arm aims to evaluate the impact of follicular-phase-focused training on neuromuscular performance, leveraging the potential effects of elevated estrogen levels during this phase.
Intervention:
Resistance Training Program: 13 weeks, 2 sessions per week, with higher intensity training scheduled during the follicular phase (early and late) and reduced intensity during the luteal phase.
干预措施: Resistance periodized training program (N-PF) (Other)
N-PL (Natural Cycle - Luteal Phase-Intensified Training)
Description: Female athletes with natural menstrual cycles who undergo a resistance training program with increased intensity during the luteal phase and reduced intensity during the follicular phase. This approach assesses the impact of training when progesterone levels are elevated.
Intervention:
Resistance Training Program: 13 weeks, 2 sessions per week, with higher intensity training during the luteal phase (early and late) and reduced intensity during the follicular phase.
干预措施: Resistance peioridized training program (N-PL) (Other)
N-C (Natural Cycle - Continuous Training)
Description: Female athletes with natural menstrual cycles who participate in a continuous intensity training program across all phases of the menstrual cycle. This group provides a comparison to determine the effects of a non-phase-specific training protocol on neuromuscular function.
Intervention:
Resistance Training Program: 13 weeks, 2 sessions per week, maintaining a consistent training intensity across both follicular and luteal phases.
干预措施: Continuous resistance training program (C) (Other)
OCP-C (Oral Contraceptive - Continuous Training, Control Group)
Description: Female athletes using oral contraceptives, following a continuous intensity training program regardless of menstrual phase. This group serves as a control, providing insight into the neuromuscular effects of training under the hormonal conditions set by oral contraceptive use.
Intervention:
Resistance Training Program: 13 weeks, 2 sessions per week, with continuous intensity across all training sessions due to the stable hormonal environment induced by oral contraceptives.
干预措施: Continuous resistance training program (C) (Other)
结局指标
主要结局
Maximal knee extensor strenght
时间窗: From baseline assessment prior to intervention to post-intervention at 13 weeks.
Description: This outcome measure assesses the maximal isokinetic strength of the knee extensor muscles, measured as peak torque (rotational force) in Newton-meters (Nm), using an isokinetic dynamometer. Scoring and Interpretation: Higher scores indicate greater strength, with no theoretical upper limit as scores are determined by the individual's maximal voluntary contraction. Typical Range: In athletic populations, peak torque values generally range from 100 to 250 Nm, but individual results may vary based on factors like muscle size and training status. Criteria for Change: An improvement in peak torque post-intervention indicates a positive neuromuscular adaptation to the training program. This measure quantifies changes in lower limb strength over time, allowing comparison of neuromuscular adaptations between menstrual phase-aligned and continuous training groups.
次要结局
- Rate of Force Development (RFD)(From baseline assessment prior to intervention to post-intervention at 13 weeks)
- Active muscle stiffness(From baseline assessment prior to intervention to post-intervention at 13 weeks.)
- Voluntary Muscle Activation (%AV)(From baseline assessment prior to intervention to post-intervention at 13 weeks.)
- Vertical Jump Height (Countermovement Jump - CMJ)(From baseline assessment prior to intervention to post-intervention at 13 weeks.)
研究者
Manon DAUVERGNE
PhD Candidate
Universite de La Reunion