Diabetes Follow-up Study for REduction of cardiovAscular outcoMes: a Coronary Computed Tomographic Angiography Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 511
- 试验地点
- 1
- 主要终点
- The change in coronary atherosclerosis detected by initial and follow-up CCTA
研究概览
简要总结
The purpose of this study is to evaluate the natural history of coronary atherosclerosis development and progression over time by CCTA and to identify risk factors attributable to the development of coronary atherosclerosis in a Korean DM population.
详细描述
Patients with diabetes mellitus, who underwent initial CCTA (coronary computed tomographic angiography) at the Diabetes Center of the Asan Medical Center between February 2008 and June 2012, will be evaluated for inclusion in the study. All DREAM-CCTA study patients will undergo follow-up CCTA based on order from their primary physician. CCTA and demographic data, medical history, cardiovascular risk factors, and laboratory data was collected in case report forms at the time of the initial CCTA and at the time of follow-up CCTA.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 19 years or older
- •Asymptomatic patients with type 2 DM who had undergone initial CCTA evaluation at the Diabetes Center of the Asan Medical Center between February 2008 and June 2012
- •Willing and able to provide informed written consent
排除标准
- •Blood test results that the Creatinine level exceeds 1.5 mg/dL
- •A person with a history of anaphylaxis or allergic shock associated with a contrast medium
- •Pregnant women
- •Unable to undergo follow-up CCTA
- •Uninterpretable CCTA
结局指标
主要结局
The change in coronary atherosclerosis detected by initial and follow-up CCTA
时间窗: about 10 years after first CCTA
the natural history of coronary atherosclerotic plaque development and progression over time by CCTA
次要结局
未报告次要终点
研究者
Seung-Whan Lee, M.D., Ph.D.
Part of cardiology, Principal Investigator, associate professor
Asan Medical Center