Community Burden of Mycoplasma Genitalium Infection and Its Implications for Test-and-treat Strategies
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 920
- 试验地点
- 1
- 主要终点
- prevalence of MG infection
研究概览
简要总结
Objective: To assess the burden and the transmission dynamics of Mycoplasma genitalium (MG) infection in men who have sex with men in Hong Kong.
Design and setting: involving a) a cross-sectional study (completion of an online self-administered survey, followed by self-sampling for testing in the laboratory, and performance of HIV self-test); b) a mathematical modelling study to simulate the transmission dynamics of MG infection and resistant MG infection and compare the impacts of test-and-treat strategies.
Participants: Around 920 men who have sex with men would be recruited
详细描述
Cross-sectional study: A total of 920 men who have sex with men aged 18 or above and normally living in Hong Kong would be recruited. Eligible participants would be asked to complete a self-administered online survey, submit self-collected urine specimen and rectal swabs for Chlamydia trachomatis, Neisseria gonorrhoeae, and Mycoplasma genitalium testing in the laboratory, and submit HIV self-test results.
Mathematical modelling study: A compartmental model would be constructed to simulate the transmission dynamics of MG infection and resistant MG infection, and analyse the impact of different test-and-treat strategies.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •men who have sex with men aged 18 or above, normally living in Hong Kong, and could communicate in written and spoken English or Chinese
排除标准
- •cannot provide consent
结局指标
主要结局
prevalence of MG infection
时间窗: 1 year
detection of MG infections in self-collected samples divided by the total number of samples collected
prevalence of MG resistance mutations
时间窗: 1 year
detection of MG resistance mutations macrolide/fluoroquinolone in MG positive samples divided by the total number of MG positive samples
次要结局
- prevalence of CT infection(1 year)
- prevalence of NG infection(1 year)
- co-infection of STIs(1 year)
- history of STI and HIV testing(ever)
研究者
Ngai Sze WONG
Assistant Professor
Chinese University of Hong Kong