NL-OMON31950尚未招募不适用
Effect of intrapulmonary administration of recombinant human activated protein C on local coagulation and inflammation after bronchial instillation of lipopolysaccharide in humans - Effect of intrapulmonary rhAPC on coagulation and inflammation after LPS
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 52
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Male subjects between 18 and 35 years of age
- •No clinically significant findings during physical examination and hematological and biochemical screening
- •Normal spirometry
- •Able to communicate well with the investigator and to comply with the requirements of the study
- •No medication
- •Written informed consent
排除标准
- •Known diseases
- •A history of smoking within the last six months, or regular consumption of greater than three units of alcohol per day
- •Administration of any investigational drug within 30 days of study initiation
- •Donation of blood within 60 days, or loss of greater than 400 ml of blood within 12 weeks of study initiation
- •History of enhanced bleeding tendency
- •History of heparin-induced thrombocytopenia
- •History of serious drug-related reactions, including hypersensitivity
研究者
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