Epidural labor analgesia evaluation of efficacy of magnesium sulphate as an adjuvant to Ropivacaine and fentanyl mixture
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- To compare onset of analgesia between both groups
研究概览
简要总结
A STUDY TITLED ’EPIDURAL LABOR ANALGESIA -EVALUATION OF EFFICACY OF MAGNESIUM SULPHATE AS AN ADJUVANT TO ROPIVACAINE AND FENTANYL MIXTURE ’ WAS CARRIED OUT IN GOVERNMENT GENERAL HOSPITAL,KADAPA DURING THE PERIOD FROM OCTOBER 2022-MARCH 2024
THIS STUDY INCLUDED 80 PRIMI PARTURIENTS DIVIDED RANDOMLY INTO TWO GROUPS EACH 40 PATIENTS .IN GROUP A PARTURIENTS RECEIVED TOTAL VOLUME OF 12 ML OF 0.125% ROPIVACAINE PLUS 25MCG FENTANYL FOR EPIDURAL LABOR ANALGESIA.ADITIONALLY,AN EPIDURAL TOP UP OF 9ML OF 0.125% ROPIVACAINE WAS ADMINISTERED WHEN THE NUMERICAL RATING SCALE SCORE WAS MORE THAN 3.IN CONTRAST GROUP B RECEIVED THE SAME VOLUME OF 12 ML OF 0.125% ROPIVACAINE PLUS 25MCG FENTANYL AND 50MG MAGNESIUM SULPHATE FOR EPIDURAL LABOR ANALGESIA.SIMILARLY,AN EPIDURAL TOP UP OF 9ML OF 0.125% ROPIVACAINE WAS ADMINISTERED WHEN THE NRS SCORE WAS MORE THAN 3.
DEMOGRAPHIC DATA WERE COMPARABLE IN BOTH GROUPS .OUR STUDY MONITORED PARAMETERS INCLUDING ONSET AND DURATION OF ANALGESIA ,NRS SCORES ,NUMBER OF TOP UPS ,MATERNAL EXPULSIVE EFFORTS,MODE OF DELIVERY,APGAR SCORES AND HEMODYNAMIC VARIABLES.
FINDINGS REVEALED A SIGNIFICANTLY FASTER ONSET OF ANALGESIA IN GROUP B COMPARED TO GROUP A WITH SIGNIFICANTLY LONGER DURATION OF ANALGESIA IN GROUP B AS WELL.MATERNAL EXPULSIVE EFFORTS AND MODE OF DELIVERY WERE COMPARABLE BETWEEN BOTH GROUPS.ADDITIONALLY THERE WERE NO STASTICAL DIFFERENCE IN APGAR SCORES AT 1 MINUTE AND 5 MINUTES BETWEEN TWO GROUPS
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 33.00 Year(s)（—）
- 性别
- Female
入选标准
- •Primi parturient American society of anaesthesiologists physiological status II Cervical dilatation with 3 cm.
排除标准
- •Parturients with bleeding disorders Parturients with local or systemic sepsis Parturients with known hypersensitivity to study drugs Parturients with spinal deformities those who has undergone spinal surgeries Parturient’s with PIH CPD breech presentation multiparty ,GDM ,multiple or high risk surgeries.
结局指标
主要结局
To compare onset of analgesia between both groups
时间窗: 1,3,5 ,10 mins
次要结局
- To compare duration of analgesia between two groups(To detect difference in numerical rating scale between two groups)
研究者
Veeramalla Pooja
Government Medical college