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临床试验/NCT01774461
NCT01774461已完成不适用

Influence of Remote Ischemic Preconditioning on Cardiac Function After Endurance Exercise

Maastricht University Medical Center1 个研究点 分布在 1 个国家目标入组 29 人开始时间: 2013年3月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
29
试验地点
1
主要终点
Serum concentrations of cardiac troponins

研究概览

简要总结

The aim of this study is to investigate the effect of remote ischemic preconditioning on biochemical and functional indices of cardiac function induced by a 30 km run in healthy trained long distance runners.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Single (Investigator)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Informed consent
  • •Age between 18 and 65 years
  • •Endurance-trained (two or more training sessions per week)

排除标准

  • •Not applicable

研究组 & 干预措施

Sham RIC

No Intervention

Control treatment (sham RIC) will consist of four 5-minute simulated inflations of a blood pressure cuff placed on the upper arm. The inflations will be separated by 5-minute periods when the blood pressure cuff will be deflated.

Remote ischemic conditioning

Active Comparator

Blood pressure cuff placed on upper arm and inflated to 200mmHg for 5 minutes then deflated for 5 minutes - this cycle is repeated a total of 4 times.

干预措施: Remote ischemic preconditioning (Other)

结局指标

主要结局

Serum concentrations of cardiac troponins

时间窗: 6 hours, 2 hourly time intervals

次要结局

  • Indices of cardiac function measured by echocardiography(2 hours post-exercise)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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