Influence of Remote Ischemic Preconditioning on Cardiac Function After Endurance Exercise
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 29
- 试验地点
- 1
- 主要终点
- Serum concentrations of cardiac troponins
研究概览
简要总结
The aim of this study is to investigate the effect of remote ischemic preconditioning on biochemical and functional indices of cardiac function induced by a 30 km run in healthy trained long distance runners.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Informed consent
- •Age between 18 and 65 years
- •Endurance-trained (two or more training sessions per week)
排除标准
- •Not applicable
研究组 & 干预措施
Sham RIC
Control treatment (sham RIC) will consist of four 5-minute simulated inflations of a blood pressure cuff placed on the upper arm. The inflations will be separated by 5-minute periods when the blood pressure cuff will be deflated.
Remote ischemic conditioning
Blood pressure cuff placed on upper arm and inflated to 200mmHg for 5 minutes then deflated for 5 minutes - this cycle is repeated a total of 4 times.
干预措施: Remote ischemic preconditioning (Other)
结局指标
主要结局
Serum concentrations of cardiac troponins
时间窗: 6 hours, 2 hourly time intervals
次要结局
- Indices of cardiac function measured by echocardiography(2 hours post-exercise)
