临床试验/CTRI/2019/07/020113

CTRI/2019/07/020113招募中未知

A PROSPECTIVE OBSERVATIONAL STUDY COMPARING RITUXIMAB , TACROLIMUS AND MODIFIED PONTICELLI REGIMEN IN THREE DIFFERENT TREATMENT COHORTS OF PRIMARY MEMBRANOUS NEPHROPATHY

IPGMER AND SSKM HOSPITAL KOLKATA0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

阶段: 未知
状态: 招募中
发起方

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

暂无简介。

研究设计

研究类型: Observational

入排标准

入选标准

•1.Biopsy proven PMN of age group 18-70 years, fulfilling the criteria for immunosuppression therapy .
•2.Fulfilling the criteria for immunosuppression therapy - Urinary protein excretion persistently exceeds 4 g/d AND remains at over 50% of the baseline value AND does not show progressive decline during antihypertensive and antiproteinuric therapy during an observation period of at least 6 months or severe disabling or life threatning symptoms related to the nephrotic syndrome.
•3.SCr has risen by 30% or more within 6 to 12 months from the time of diagnosis but the eGFR is not less than 25 ml/min per 1.73m2 AND this change is not explained by superimposed complications.

排除标准

•1.Patients with active infection.
•2.Diabetes mellitus.
•3.Hepatitis B/C or human immunodeficiency virus infection.
•4.Liver function abnormalities.
•5.Neoplasia.
•6.Chronic Diarrhoea.
•7.Pregnancy.
•8.Patients not willing for contraception.

研究者

发起方

IPGMER AND SSKM HOSPITAL KOLKATA

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