Efficacy of Drinking Water on Transit Time and Complete Examination Rate During Capsule Endoscopy
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- gastric transit time
研究概览
简要总结
The aims of this study are to evaluate the effect of early drinking water after the capsule ingestion on the gastrointestinal transit and image quality of capsule endoscopy.
详细描述
Capsule endoscopy has been a significant technologic advancement that has allowed the direct examination of mucosa throughout the entire small intestine in a noninvasive fashion; and it has become the primary technique for imaging the small bowel. However, as imaging time is limited to about 8 hours, a prolonged transit of the capsule endoscope in the stomach may result in an incomplete small bowel transit (i.e. failure of the capsule to reach the cecum). Delayed transit time of stomach may be responsible for the failure of capsule endoscopy to visualize the distal portions of the small bowel, and potentially may result in the inability to identify small-bowel pathology in these areas. Previous study showed that drinking water might improve completion rate of capsule endoscopy. And bowel preparation of clear liquids may improve image quality of small bowel mucosa. The aim of this study was to assess the effect of drinking water on the transit time,completion rate and image quality of capsule endoscopy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients aged 18-80 years undergoing capsule endoscopy
排除标准
- •Patients with suspected intestinal obstruction, intestinal diverticulum, stricture or fistula
- •previous gastric or small-bowel surgery
结局指标
主要结局
gastric transit time
时间窗: 3 months
the time between the first gastric image and the first duodenal image
small-bowel transit time
时间窗: 3 months
the imaging time of capsule endoscopy in the small bowel
次要结局
- diagnostic yields(3 months)
- complete examination rate of the small bowel(3 months)
- image quality(3 months)
研究者
Xiuli Zuo
doctoral supervisor of Qilu Hospital gastroenterology department
Shandong University
