The Bilateral Deficit Phenomenon, Functional and Dynamometric Assessment in Postmenopausal Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Assess the maximum force of lower limbs during bilateral and unilateral contraction
研究概览
简要总结
The bilateral deficit phenomenon (BLD) is defined as an inability of the neuromuscular system to generate maximal force when two homonymous limb operate simultaneously (bilateral contraction) with respect to the force developed when both limbs acts separately (unilateral contraction). From an applied perspective, movement patterns of bilateral homonymous limb are often developed during activities of day living, e.g. rising from a chair or opening a jar. The BLD can be considered an intrinsic property of the human neuromuscular system but could be enough important to constitute a performance-limiting factor for postmenopausal women that involves a degenerative loss of muscular strength. Therefore, a specific analysis of this phenomenon and its relation with activities of daily living, such as climbing a step and rising from a chair, is crucial for detecting variables of neuromuscular performance and develop strategies to minimize the loss of strength.
详细描述
- 20 postmenopausal women unexperience in strength training or resistance training, without musculoskeletal, neurological diseases, and cardiovascular limiting-diseases were recruited.
- Maximum strength of lower limbs during leg-press exercise was measured for future analysis.
- The force-time curves were measured during climbing a step and rising from a chair.
- A fragility phenotype test was applied to the subjects to determine frailty phenotype classification, including; weight loss of greater than 10 lbs in the past 12 months, maximal handgrip strength, time to walk 15-ft at usual pace, self-reported leisure time physical activity, and self-reported exhaustion.
- The anthropometric measurements were performed by dual energy X-ray absorptiometry.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 50 Years 至 70 Years(Adult, Older Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Postmenopausal women
排除标准
- •Unexperienced in strength training or resistance training.
- •Not musculoskeletal diseases.
- •Not neurological diseases.
- •Not cardiovascular limiting-diseases.
- •Not fragility or pre-fragility phenotype.
结局指标
主要结局
Assess the maximum force of lower limbs during bilateral and unilateral contraction
时间窗: Screening visit
Assess the force-time curve during climbing a step
时间窗: Screening visit
Assess the force-time curve during climbing rising from a chair
时间窗: Screening visit
Assess bone mineral-free lean tissue mass by dual energy X-ray absorptiometry
时间窗: Screening visit
Assess the fragility phenotype of the subjects
时间窗: Screening visit
Assess the rate of force developed in time intervals (0-50, 50-100, 100-150ms) of lower limbs during bilateral and unilateral contraction
时间窗: Screening visit
Assess fat-tissue mass and lean-tissue mass composition
时间窗: Screening visit
次要结局
未报告次要终点
研究者
Juan Diego Ruiz-Cárdenas
BSc, MSc
Universidad Católica San Antonio de Murcia
