NCT07660484尚未招募不适用
ASCO Study: Link Between ASCorbemia Level and Osteoporosis
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 40
- 试验地点
- 1
研究概览
简要总结
This monocentric observational study aims to evaluate the association between plasma vitamin C levels (ascorbemia) and the presence of osteoporotic vertebral fractures in patients with osteoporosis. Forty participants will be enrolled at the Rheumatology
详细描述
- . Patients in group A or B will be seen in consultation or admitted by one of the medical team members among the investigators.
- . After signing the informed consent and checking the inclusion criteria, the blood sample will be taken by a member of the nursing team of the department.
- . The collection tube will then be placed in an opaque cooler, refrigerated with ice, and transported to the university hospital's biochemistry lab (routine assay).
- . Next, the collection of planned clinical and paraclinical data:
- Diet and risk factors for vitamin C deficiency:
- Demographic data - osteoporosis risk factors
- Bone status
- . Once all the data is collected, we will carry out the statistical analyses, then draft the article, and finally publish it.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Men aged 50 yars or older ;
- •Postmenopausal women ;
- •Afilliated with a health insurance and system ;
- •Written informed consent obtained.
- •Group 1 : Clincal osteoporotic vertebral fracture confirmed by imaging within the previous month ; Followed in the Rheumatology department for management of vertebral fracture.
- •Group 2 : Densitometric osteoporosis (T-score ≤ -2.5) ; No history of severe osteoporotic fracture ; No history of clinical or morphometric vertebral fracture.
排除标准
- •Legal protection measure (guardianship, curatorship);
- •inability to provide informed consent ;
- •refusal to participate ;
- •Vertebral fracture related to tumor,
- •infection, trauma or non osteoporotic causes ;
- •asymptomatic vertebral fracture discovered incidentally ;
- •Severe densitometric osteoporosis for group 2 ;
- •Previous severe osteoporotic fracture for group B.
研究组 & 干预措施
Osteoporosis with vertebral fracture
Experimental
Blood sampling for measurement of plasma vitamin C concentration (ascorbemia) in patient with osteoporosis and recent clincal vertebral fracture.
干预措施: Plasma vitamin C assessment (Diagnostic Test)
Non-severe osteoporosis
Experimental
Blood sampling for measurement of plasma vitamin C concentration (ascorbemia) in patient with osteoporosis without vertebral fracture.
干预措施: Plasma vitamin C assessment (Diagnostic Test)
研究者
研究点 (1)
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