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临床试验/NCT02292992
NCT02292992Unknown不适用

The Difference of Lung Volume Change Detected by Electrical Impedance Tomography (EIT) Between Noninvasive Positive-pressure Ventilation (NIPPV) Support by Nasal Pillow and High Flow Nasal Cannula in Post-extubation Patients

Mackay Memorial Hospital1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2014年12月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
40
试验地点
1
主要终点
• End-expiratory lung volume (EELV) determined by electrical impedance tomography after high flow nasal cannula and nasal pillow CPAP

研究概览

简要总结

The difference of lung volume change will be monitored by electrical impedance tomography before and after use of noninvasive positive pressure ventilation by nasal pillow and high flow nasal cannula in post-extubation patients.

详细描述

Electrical impedance tomography can effectively monitor the lung volume change in ICU patients who were under mechanical ventilator or noninvasive positive pressure ventilator support. Continuous positive airway pressure (CPAP) support by nasal pillow and high flow nasal cannula can improve inspiratory function in extubated patients . However, the extent of lung volume change or functional residual volume (FRC) change by using these two devices were never surveyed before in extubated patients. The investigators will check end-expiratory lung volume (EELV) ,anterior, medio-anterior, medio-posterior and posterior EELV by electrical impedance tomography after use of these two devices in extubated patients.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Any extubated patients after tolerating spontaneous breathing trial

排除标准

  • Presence of tracheostomy
  • Recent facial trauma
  • Active gastro-intestinal bleeding
  • Do-not-intubate status and
  • Planned use of BiPAP after extubation.
  • Patients with unstable spinal lesions or fractures.
  • Patients with a cardiac pacemaker
  • Burn injury with skin defect

研究组 & 干预措施

Nasal pillow CPAP

Experimental

Nasal pillow CPAP

干预措施: Nasal Pillow CPAP (Device)

结局指标

主要结局

• End-expiratory lung volume (EELV) determined by electrical impedance tomography after high flow nasal cannula and nasal pillow CPAP

时间窗: at day 1

次要结局

  • Anterior, medio-anterior, medio-posterior and posterior EELV at each time(at day 1)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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