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临床试验/NCT05688150
NCT05688150已完成不适用

Prevalence and Associated Factors of Sarcopenia Among Elderly Patients in Osteoporosis Clinic

Kowloon Hospital, Hong Kong1 个研究点 分布在 1 个国家目标入组 94 人开始时间: 2022年6月20日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
94
试验地点
1
主要终点
Prevalence of Sarcopenia

研究概览

简要总结

This was a cross-sectional study. Patients who attended the osteoporosis clinic of Kowloon Hospital from June to December 2022 were recruited.

Grip strength and appendicular skeletal muscle mass index were measured with a Jamar dynamometer and a bioimpedance analyser. Since most patients in our clinic are of Chinese ethnicity, the diagnostic criteria in the Consensus Update on Sarcopenia Diagnosis and Treatment by the Asian Working Group for Sarcopenia in 2019 was utilised. The diagnosis of sarcopenia was established by the presence of both low grip strength (Male: < 28 kg, Female < 18 kg) and low appendicular skeletal mass (Male: < 7.0 kg/m2, Female: < 5.7 kg/m2)

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
60 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients aged 60 years old or above
  • Diagnosed with osteoporosis by: Fragility fracture or T-score ≤-2.5 SDs at any site on DXA scan and;
  • Able to read and write Chinese

排除标准

  • Unable to maintain standing posture for bioimpedance analysis
  • Modified Functional Ambulation Classification (MFAC) ≤ IV
  • Incompetent in giving consent
  • Unable to follow instructions
  • Implanted with metal in any of four limbs
  • Implanted with pacemaker, implantable cardioverter defibrillator or any other types of electrical device

结局指标

主要结局

Prevalence of Sarcopenia

时间窗: June - December 2022

The diagnosis of sarcopenia would be established by the co-existence of low grip strength and low appendicular skeletal muscle mass.

Grip strength

时间窗: June - December 2022

Grip strength would be measured with Jamar digital dynamometer.

Appendicular Skeletal Muscle Mass Index

时间窗: June - December 2022

Appendicular Skeletal Muscle Mass Index would be measured with bioimpedance analyzer.

次要结局

  • Association between BMI and Sarcopenia.(June - December 2022)
  • Association between Frailty and Sarcopenia.(June - December 2022)
  • Association between Bone Mineral Densities and Sarcopenia(June - December 2022)
  • Association between Charlson Comorbidities Index and Sarcopenia(June - December 2022)

研究者

发起方
Kowloon Hospital, Hong Kong
申办方类型
Other
责任方
Principal Investigator
主要研究者

Leung Hin Cheung

Principal Investigator

Kowloon Hospital, Hong Kong

研究点 (1)

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