Efficacy of subglottic suctioning in the prevention of ventilator associated pneumonia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 172
- 试验地点
- 1
- 主要终点
- The primary outcome will be the incidence of Ventilator Associated Pneumonia (VAP).
研究概览
简要总结
Recruited 172 subjects will be randomised into two groups- groupC who will receive regular endotracheal tube and group S who will receive endotracheal tube with a port for subglottic suctioning. The primary outcome is to note the incidence of ventilator associated pneumonia between the two groups. The objective measures noted for primary outcome are : temperature, total count, secretions (clear/purulent),rales/bronchial breath sounds, inspired oxygen concentration (FiO2), PEEP, Chest X ray (infiltrate/consolidation) , microbiological analysis. These are recorded every day from Day 1 to Day14. The secondary outcome is duration of ventilation, duration of ICU stay, addition of new antibiotics and 30 day mortality. Data collected will be statistically analysed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients aged between 18-70 years who are expected to be ventilated for a duration of more than 72 hours.
排除标准
- •1.Patients with pneumonia, Acute respiratory distress syndrome 2.Patients suspected to have pulmonary aspiration 3.Intubated patients received from another hospital.
结局指标
主要结局
The primary outcome will be the incidence of Ventilator Associated Pneumonia (VAP).
时间窗: Everyday at 10 AM from Day 1 to Day 14 the objective parameters are assessed
次要结局
- duration of ventilation, duration of ICU stay, addition of new antibiotics and 30 day mortality(Everyday at 10 AM from Day 1 to Day 30 the parameters are assessed)