The effects of plant sterol and stanol esters on serum oxyphytosterol concentrations in healthy human subjects - Phytosterols and oxyphytosterol concentrations

niversiteit Maastricht0 个研究点目标入组 48 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•- unstable body weight (weight gain or loss > 3 kg in the past two months)
•- active cardiovascular diseases like congestive heart failure or recent (<6 months) event (acute myocardial infarction, cerebral vascular incident)
•- severe medical conditions that might interfere with the study such as epilepsy, asthma, chronic obstructive pulmonary disease, inflammatory bowel disease and rheumatoid arthritis)
•- indication for treatment with cholesterol-lowering drugs according to the Dutch Cholesterol Consensus
•- use of medication such as corticosteroids, diuretics or lipid lowering therapy
•- abuse of drug or alcohol (>21 units per week)
•- not willing to stop the consumption of vitamin supplements, fish oil capsules or products rich in sterol or stanol esters 4 weeks before the start of the study (wash-in period)
•- use of an investigational product within another biomedical study within the previous month
•- pregnant or breast-feeding women
•- not willing to give up being a blood donor (or having donated blood) from 8 weeks before the start of the study and during the study
•- current smoker
•- anemia. with a Hb-level below 7.5 mmol/L for men and below 7.0 mmol/L for women, as indicated by the blood bank of Maastricht

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