Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 768
- 试验地点
- 1
- 主要终点
- Tobacco Abstinence
研究概览
简要总结
The goal of this clinical trial is to evaluate the effectiveness and implementation of a pharmacist-delivered MTM (medication therapy management) approach, called QuitAid, to quitting cigarette smoking in rural Appalachia.
The main questions it aims to answer are:
- Is QuitAid, alone or combined with other quitting tobacco treatments, effective?
- What makes QuitAid easy or hard to carry out? Is it cost effective? Is it easy to maintain?
Treatment:
All participants will be given at least 4 weeks of the nicotine patch.
Some participants will be randomized (like the flip of a coin) to receive additional treatments (listed below).
These groups will be compared to each other to see which combination works best to help them quit smoking.
- Smokefree TXT - a texting program that helps people quit smoking
- Tobacco quitline - 4 phone sessions to help people quit smoking
- 8 weeks of NRT (nicotine replacement therapy in the form of nicotine patches or nicotine patches and lozenge) medication instead of 4 weeks
- QuitAid - An MTM program given by the patient's pharmacist. This is a quitting smoking coaching program
- Nicotine patch AND nicotine lozenge instead of just nicotine patches
详细描述
The proposed study uses a mixed-method design to evaluate the effectiveness and implementation of a pharmacist-delivered MTM (Medication Therapy Management) approach, called QuitAid, to smoking cessation in rural Appalachia. Aim 1 of this project will evaluate the effectiveness of QuitAid and standard, evidence-based tobacco treatments on cessation within an MTM pharmacist-delivered approach. Aim 2 will assess implementation, including relative cost of QuitAid, as well as standard, evidence-based tobacco treatments through an ask-advise-connect model, in community pharmacies, and will examine facilitators and barriers to reach, adoption, and maintenance of QuitAid as well as standard, evidence-based tobacco treatments through an ask-advise-connect method in community pharmacies.
Smokers (n=768) recruited through 14 community pharmacies in rural Appalachia will be randomized in a 2x2x2x2x2 full factorial experiment to the following five treatments: (1) QuitAid Intervention (Yes vs. No), (2) tobacco quitline (Yes vs. No), (3) SmokefreeTXT through the National Cancer Institute's (NCI) Smokefree.gov initiative (Yes vs. No), (4) Combination NRT Lozenge + NRT Patch (vs. NRT patch alone), and/or (5) 8 weeks of NRT (vs. standard 4 weeks). Following the experimental trial, we will use an implementation science approach to assess implementation, including relative cost, as well as facilitators and barriers of reach, adoption, and maintenance of QuitAid and standard, evidence-based tobacco treatments through an ask-advise-connect method in community pharmacies (Aim 2).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Study participants will be rural cigarette smokers from Virginia, Tennessee, Kentucky and North Carolina who visit one of the participating study pharmacies. Pharmacies will be located in rural geographic areas of the Central and South Central subregions of Appalachia that include Virginia, Tennessee, Kentucky and North Carolina, as defined by the USDA Rural-Urban Continuum Codes (RUCC) 4-9, Rural-Urban Commuting Area (RUCA) codes 4-10, or Frontier and Remote (FAR) areas level
- •No exclusionary criteria are based on race, gender, or age.
- •Inclusion Criteria include:
- •must be 18 years of age and older
- •must be able to read, speak, and understand English
- •must report smoking at least 5 cigarettes per day for the past 6 months (regardless of non-cigarette tobacco product use)
- •must be willing to set a quit date within the next 30 days
- •must own a cell phone
- •must be willing and able to use NRT in the form of patch or lozenge
- •Not be pregnant or planning to be pregnant in the next 6 months.
排除标准
- •are pregnant women (self-reported), breastfeeding, planning to become pregnant during the next 6 months
- •have a medical contraindication to NRT (e.g., past 30 days, heart attack or stroke; past 6 months, serious or worsening angina, very rapid or irregular heartbeat requiring medication)
研究组 & 干预措施
QuitAid, 8 weeks, Patch + Lozenge
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist and 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge.
干预措施: 8 Weeks Nicotine Lozenge (Drug)
QuitAid, 4 weeks, Patch + Lozenge, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge, and a Quitline intervention
干预措施: QuitAid (Behavioral)
QuitAid, 8 weeks, Patch, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a Quitline intervention
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a Quitline intervention
干预措施: QuitAid (Behavioral)
QuitAid, 8 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Tobacco Quitline (Behavioral)
QuitAid, 4 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: 4 weeks of Nicotine lozenge (Drug)
QuitAid, 4 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
8 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
8 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Smokefree TXT (Behavioral)
8 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Tobacco Quitline (Behavioral)
4 weeks, Patch + Lozenge, QuitLine
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a Quitline Intervention.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
4 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge and a texting intervention to help quit smoking.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
8 weeks, Patch + Lozenge
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge.
干预措施: 8 Weeks Nicotine Lozenge (Drug)
8 weeks, Patch
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
4 weeks, Patch + Lozenge
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge.
干预措施: 4 weeks of Nicotine lozenge (Drug)
4 weeks, Patch + Lozenge
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
4 weeks, Patch
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist and 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch.
干预措施: QuitAid (Behavioral)
QuitAid, 4 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 4 weeks, Patch + Lozenge
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist and 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge.
干预措施: 4 weeks of Nicotine lozenge (Drug)
4 weeks, Patch, QuitLine
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a Quitline Intervention.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch + Lozenge, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge, and a Quitline intervention
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
4 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 4 weeks, Patch + Lozenge
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist and 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge.
干预措施: QuitAid (Behavioral)
QuitAid, 4 weeks, Patch + Lozenge
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist and 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch + Lozenge
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist and 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch + Lozenge
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist and 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge.
干预措施: QuitAid (Behavioral)
QuitAid, 4 weeks, Patch + Lozenge, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge, and a Quitline intervention
干预措施: 4 weeks of Nicotine lozenge (Drug)
QuitAid, 4 weeks, Patch + Lozenge, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge, and a Quitline intervention
干预措施: Tobacco Quitline (Behavioral)
QuitAid, 4 weeks, Patch + Lozenge, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge, and a Quitline intervention
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch + Lozenge, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge, and a Quitline intervention
干预措施: QuitAid (Behavioral)
QuitAid, 8 weeks, Patch + Lozenge, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge, and a Quitline intervention
干预措施: Tobacco Quitline (Behavioral)
QuitAid, 8 weeks, Patch + Lozenge, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and the nicotine lozenge, and a Quitline intervention
干预措施: 8 Weeks Nicotine Lozenge (Drug)
QuitAid, 4 weeks, Patch
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist and 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch.
干预措施: QuitAid (Behavioral)
QuitAid, 4 weeks, Patch
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist and 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist and 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a Quitline intervention
干预措施: Tobacco Quitline (Behavioral)
QuitAid, 4 weeks, Patch, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a Quitline intervention
干预措施: QuitAid (Behavioral)
QuitAid, 4 weeks, Patch, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a Quitline intervention
干预措施: Tobacco Quitline (Behavioral)
QuitAid, 4 weeks, Patch, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a Quitline intervention
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 4 weeks, Patch, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a texting intervention to help quit smoking.
干预措施: QuitAid (Behavioral)
QuitAid, 4 weeks, Patch, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a texting intervention to help quit smoking.
干预措施: Smokefree TXT (Behavioral)
QuitAid, 4 weeks, Patch, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a texting intervention to help quit smoking.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a texting intervention to help quit smoking.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a texting intervention to help quit smoking.
干预措施: QuitAid (Behavioral)
QuitAid, 8 weeks, Patch, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a texting intervention to help quit smoking.
干预措施: Smokefree TXT (Behavioral)
QuitAid, 8 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a texting intervention to help quit smoking.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a texting intervention to help quit smoking.
干预措施: QuitAid (Behavioral)
QuitAid, 8 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a texting intervention to help quit smoking.
干预措施: Smokefree TXT (Behavioral)
QuitAid, 8 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a texting intervention to help quit smoking.
干预措施: 8 Weeks Nicotine Lozenge (Drug)
QuitAid, 4 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a texting intervention to help quit smoking.
干预措施: 4 weeks of Nicotine lozenge (Drug)
QuitAid, 4 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a texting intervention to help quit smoking.
干预措施: QuitAid (Behavioral)
QuitAid, 4 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a texting intervention to help quit smoking.
干预措施: Smokefree TXT (Behavioral)
QuitAid, 4 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a texting intervention to help quit smoking.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: QuitAid (Behavioral)
QuitAid, 8 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Smokefree TXT (Behavioral)
QuitAid, 8 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Tobacco Quitline (Behavioral)
QuitAid, 8 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: 8 Weeks Nicotine Lozenge (Drug)
QuitAid, 8 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
QuitAid, 8 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: QuitAid (Behavioral)
QuitAid, 8 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Smokefree TXT (Behavioral)
QuitAid, 4 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: QuitAid (Behavioral)
QuitAid, 4 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Smokefree TXT (Behavioral)
QuitAid, 4 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Tobacco Quitline (Behavioral)
QuitAid, 4 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: QuitAid (Behavioral)
QuitAid, 4 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Smokefree TXT (Behavioral)
QuitAid, 4 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive QuitAid, a medication therapy management delivered by their pharmacist, 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Tobacco Quitline (Behavioral)
8 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Tobacco Quitline (Behavioral)
8 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: 8 Weeks Nicotine Lozenge (Drug)
8 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
8 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Smokefree TXT (Behavioral)
4 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: 4 weeks of Nicotine lozenge (Drug)
4 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Smokefree TXT (Behavioral)
4 weeks, Patch + Lozenge, SmokeFree Txt, QuitLine
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Tobacco Quitline (Behavioral)
4 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Smokefree TXT (Behavioral)
4 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: Tobacco Quitline (Behavioral)
4 weeks, Patch, SmokeFree Txt, QuitLine
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, a texting intervention to help quit smoking, and a Quitline Intervention.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
8 weeks, Patch + Lozenge, QuitLine
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a Quitline Intervention.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
8 weeks, Patch + Lozenge, QuitLine
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a Quitline Intervention.
干预措施: Tobacco Quitline (Behavioral)
8 weeks, Patch + Lozenge, QuitLine
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a Quitline Intervention.
干预措施: 8 Weeks Nicotine Lozenge (Drug)
8 weeks, Patch, QuitLine
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a Quitline Intervention.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
8 weeks, Patch, QuitLine
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a Quitline Intervention.
干预措施: Tobacco Quitline (Behavioral)
4 weeks, Patch + Lozenge, QuitLine
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a Quitline Intervention.
干预措施: 4 weeks of Nicotine lozenge (Drug)
4 weeks, Patch + Lozenge, QuitLine
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge, and a Quitline Intervention.
干预措施: Tobacco Quitline (Behavioral)
4 weeks, Patch, QuitLine
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch, and a Quitline Intervention.
干预措施: Tobacco Quitline (Behavioral)
8 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge and a texting intervention to help quit smoking.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
8 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge and a texting intervention to help quit smoking.
干预措施: Smokefree TXT (Behavioral)
8 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge and a texting intervention to help quit smoking.
干预措施: 8 Weeks Nicotine Lozenge (Drug)
8 weeks, Patch, SmokeFree Txt
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and a texting intervention to help quit smoking.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
8 weeks, Patch, SmokeFree Txt
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and a texting intervention to help quit smoking.
干预措施: Smokefree TXT (Behavioral)
4 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge and a texting intervention to help quit smoking.
干预措施: 4 weeks of Nicotine lozenge (Drug)
4 weeks, Patch + Lozenge, SmokeFree Txt
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge and a texting intervention to help quit smoking.
干预措施: Smokefree TXT (Behavioral)
4 weeks, Patch, SmokeFree Txt
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and a texting intervention to help quit smoking.
干预措施: Smokefree TXT (Behavioral)
4 weeks, Patch, SmokeFree Txt
Smoking participants receive 4 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and a texting intervention to help quit smoking.
干预措施: 4 weeks of Nicotine Replacement Therapy Patch (Drug)
8 weeks, Patch + Lozenge
Smoking participants receive 8 weeks Nicotine Replacement Therapy (NRT) in the form of the nicotine patch and lozenge.
干预措施: 8 weeks of Nicotine Replacement Therapy Patch (Drug)
结局指标
主要结局
Tobacco Abstinence
时间窗: 6 months
The primary outcome is biochemically verified point prevalence (verified through a CO test via Smokerlyzer at endpoint of participation in trial) abstinence defined as no smoking (even a puff) within the past 7 days.
次要结局
- Self-Reported Tobacco Abstinence(1, 2, and 3 months)
- Adherence to assigned treatment components(1, 2, and 3 months)
- Quit Attempts(1, 2, and 3 months)
研究者
Melissa Little, PhD, MPH
Associate Professor
University of Virginia