ISRCTN22669537已完成未知
A multi-centre double blind randomised controlled trial of aspirin and/or folate supplementation for the prevention of recurrent colorectal adenoma
Cancer Research UK (CRUK) (UK)0 个研究点目标入组 1,000 人开始时间: 2001年7月1日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 1,000
研究概览
简要总结
2008 results in http://www.ncbi.nlm.nih.gov/pubmed/18022173
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Eligible patients who have had:
- •1. Removal of adenomas greater than 0.5 cm after fixation or adenomas greater than 0.7 cm at the time of removal, within the last six months
- •2. A previous history of removal of such adenomas and have had adenoma of any size removed in the six months prior to recruitment These adenomas will be histologically confirmed and removed by either colonoscopy, flexi-sigmoidoscopy or via Transanal Endoscopic Microsurgery (TEMS) procedure
排除标准
- •1. Over 75 years at time of recruitment
- •2. Serious medical conditions likely to preclude successful completion of the trial
- •3. Existing use of prescribed Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) including aspirin
- •4. Known aspirin intolerance or sensitivity
- •5. Active bleeding disorders or upper Gastrointestinal (GI) ulceration, including use of anticoagulants
- •6. Previous resection of the large bowel
研究者
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