临床试验/NCT00889525

NCT00889525已完成3 期

Study of Cabergoline in Treatment of Corticotroph Pituitary Tumor

Seth Gordhandas Sunderdas Medical College1 个研究点分布在 1 个国家开始时间: 2007年11月最近更新: 2009年4月29日

适应症

干预措施

试验速览

阶段: 3 期
状态: 已完成
发起方: Seth Gordhandas Sunderdas Medical College
试验地点: 1
主要终点: Response in term of mid night cortisol < 5.0 mcg/dl and/or Standard two day dexamethasone suppression test < 1.8 mcg/dl

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This study was designed to check the efficacy of a new oral medical drug treatment, namely Cabergoline, for the treatment of Cushing Disease due to pituitary adenoma.

Background: Cabergoline is a Dopamine 2 receptor agonist. Corticotroph adenoma has shown to have the D2 receptor in in vitro studies.

研究设计

研究类型: Interventional
分配方式: Non Randomized
干预模型: Single Group
主要目的: Treatment
盲法: None

入排标准

年龄范围: 12 Years 至 —（Child, Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Patient with Cushing's disease uncured biochemically after pituitary surgery with adenoma on histopathology

排除标准

•Patient's intolerance to drug or known sensitivity to ergot derivatives
•Pregnancy, lactation or female wishing to be pregnant
•Any serious medical illness
•Patient on any drugs known to have an interaction with cabergoline including antihypertensives like reserpine and methyl dopa, neuroleptics, metoclopramide, etc

研究组 & 干预措施

Cabergoline

Experimental

干预措施: Cabergoline (Drug)

结局指标

主要结局

Response in term of mid night cortisol < 5.0 mcg/dl and/or Standard two day dexamethasone suppression test < 1.8 mcg/dl

次要结局

未报告次要终点

研究者

发起方

Seth Gordhandas Sunderdas Medical College

申办方类型

Other

研究点 (1)

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