NCT00289367已完成1 期
Randomized Prospective Study of T3 on the Incidence of Post-Operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 280
- 试验地点
- 2
- 主要终点
- incidence of atrial fibrillation
研究概览
简要总结
The purpose of this project is to see whether treatment with a thyroid hormone, called triiodothyronine or T3, following open heart surgery reduces the risk of developing atrial fibrillation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients requiring CABG or valve repair/replacement surgery.
- •Patient must be able to provide informed consent.
排除标准
- •Patients less than 18 or over 85 years of age.
- •Patients less than 50kg or greater than 120kg.
- •Patients currently with endocrine disorders, excluding diabetes.
- •Patients currently with thyroid dysfunction (e.g., hyper- hyperthyroidism, goiter, Grave's disease), myxedema, or myxedema coma, even if treated.
- •Patients currently receiving thyroid replacement therapy.
- •Patients currently receiving Ketamine, levarterenol or dietary (non-food) iodine supplementation.
- •Patients who have received any investigational drugs within the previous one month or five half-lives of the drug.
- •Patients who are pregnant. Pregnancy testing will be done for women of child-bearing potential.
- •Patients currently in atrial fibrillation.
结局指标
主要结局
incidence of atrial fibrillation
时间窗: during hospitalization
次要结局
未报告次要终点
研究者
研究点 (2)
Loading locations...
相似试验
已完成
3 期
Efficacy and Safety Study of Talimogene Laherparepvec Compared to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) in MelanomaMelanomaNCT00769704BioVex Limited437
招募中
3 期
Platform Study of Circulating Tumor DNA Directed Adjuvant Chemotherapy in Colon Cancer (KCSG CO22-12)Colon CancerNCT05534087Seoul National University Hospital236
已完成
不适用
THIODERM ELATE for Augmentation of Very Thin, Thin, and Moderately Thick LipsLip AbnormalityNCT06135337Croma-Pharma GmbH33
已完成
3 期
TELESTAR (Telotristat Etiprate for Somatostatin Analogue Not Adequately Controlled Carcinoid Syndrome)Carcinoid SyndromeNCT01677910Lexicon Pharmaceuticals135
已完成
3 期
A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular DiseaseCardiovascular DiseasesObesityNCT05882045Eli Lilly and Company1,946