Examining Choice Architecture for Genetic Testing Decisions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,012
- 试验地点
- 2
- 主要终点
- Decisional Regret Scale (DRS)
研究概览
简要总结
The goal of this application is to gain a deeper understanding of decision-making for genetic testing and identify effective choice-architecture-based strategies to improve decisions in genetic testing. The investigators hypothesize that choice architecture (i.e. framing) affects decision-making for hypothetical genetic testing scenarios.
详细描述
After providing opt-in electronic consent, eligible consented participants will be randomized to one of two hypothetical genetic testing scenarios (rare, life-altering genetic condition or common, life-threatening genetic condition). The genetic testing scenarios include brief detailed information about genetic testing (i.e. how results may influence treatment decisions) as well as information about standard approaches to treatment. Subjects will be randomized to receive a framing conditions (e.g. choice, opt-in, opt-out, enhanced choice). Participants will select a preferred testing option to the hypothetical scenario and will complete several validated instruments.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Participant)
盲法说明
participants are blinded to arm and decision frame
入排标准
- 年龄范围
- 18 Years 至 64 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult participants (18-64 yrs) residing in North America (who are members of the Amazon Mechanical Turk platform)
排除标准
- •age <18yrs or >65yrs or residing outside of North America
结局指标
主要结局
Decisional Regret Scale (DRS)
时间窗: study completion (approximately 30 minutes)
DRS is a validated 5-item instrument, items are scored on a 1-5 scale with higher scores indicating more regret with the decision taken
Genetic testing decision
时间窗: after reading the scenario and viewing frame (approximately 10 minutes)
Opting "yes" for genetic testing or "no" refusing genetic testing
Satisfaction with Decision Scale (SWD)
时间窗: study completion (approximately 30 minutes)
SWD is a validated 6-item instrument, items are scored on a 1-5 scale with higher scores indicating greater satisfaction with the decision taken
次要结局
- Experience with genetic disease(Baseline (study onset))
- Newest Vital Sign (NVS)(study completion (approximately 30 minutes))