RBR-2nfjd5g进行中（未招募）Unknown
Evaluation of the Efficacy of two Multi-Component Oral Hygiene Schemes in patients undergoing non-surgical periodontal treatment: a double-blind randomized clinical trial
niversidade de São Paulo0 个研究点开始时间: 2023年4月13日最近更新:
试验速览
- 阶段
- Unknown
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
Both groups presented statistically significant reductions in all clinical parameters compared to baseline. The DZA/CPC+Zn group exhibited significant reductions in gingival index, gingival severity index, interproximal gingival index, plaque index and interproximal plaque index compared to the control group at 1, 3, and 6 months. Clinical assessments were not different three months after both groups re-established similar regimen with fluoride toothpaste.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18Y 至 65Y（—）
入选标准
- •men and women, between 18 and 65 years of age; availability to participate in the study; good general health (absence of any condition that, in the opinion of the principal investigator, could pose a risk to the subject during study participation. Examples include heart problems, valve/hip replacement, etc.); availability to provide information relating to your medical history; minimum of 15 permanent natural teeth (excluding third molars and teeth with crowns); diagnosis of moderate gingivitis (an initial gingival index score of at least 1.5); at least 10% of sites with bleeding on probing;
排除标准
- •presence of any oral pathology or chronic disease that, in the opinion of the main investigator, may constitute a risk for the subject during participation in the study or may modify the progression and/or response to periodontal treatment; daily use of anticonvulsants, antihistamines, sedatives, tranquilizers, anti-inflammatory medication, or analgesics in the month prior to starting the study or scheduled to start using these medications during the course of the study; participation in another clinical trial; pregnancy or lactation; allergy to oral care products to be tested in the study; prolonged use of antibiotics or mouthwashes during the three months prior to the beginning of the study; need for antibiotic prophylaxis; continued use of medications known to affect gingival tissues (i.e. calcium channel blockers, phenytoin, cyclosporine); periodontal treatment 12 months before the beginning of the study; more than two periodontal pockets (excluding pseudopockets) with bleeding on probing; smoking, history of alcohol abuse and/or drug use; existing medical condition that prohibits the individual from abstaining from eating or drinking for periods of up to 4 hours.
研究者
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