To compare the effect of intrathecal nalbuphine and fentanyl as adjuvants to bupivacaine in caesarean section.
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Sensory blockade
研究概览
简要总结
To prolong the duration of postoperative analgesia in caesarean section by adding adjuvants to bupivacaine in spinal blockade
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 35.00 Year(s)（—）
- 性别
- Female
入选标准
- •Term Pregnant females with ASA Grade I,II.
排除标准
- •1.Patient’s refusal 2.Any spine abnormality 3.Altered coagulation profile 4.Allergy to local anaesthetic 5.Recent myocardial infarction 6.Significant aortic stenosis Patients with neurological disorders Cardiac or respiratory system failure Any major hepatic or renal problem.
结局指标
主要结局
Sensory blockade
时间窗: Sensory blockade: continuously​ till onset then every 10 minutes​ till regression | Motor blockade at 5,10,15 minutes then every 10minutes till regression | 3.VAS: every 15 minutes in the first hour then hourly for 4 hours then at 12hours and 24 hours after spinal blockade
Motor blockade
时间窗: Sensory blockade: continuously​ till onset then every 10 minutes​ till regression | Motor blockade at 5,10,15 minutes then every 10minutes till regression | 3.VAS: every 15 minutes in the first hour then hourly for 4 hours then at 12hours and 24 hours after spinal blockade
VAS
时间窗: Sensory blockade: continuously​ till onset then every 10 minutes​ till regression | Motor blockade at 5,10,15 minutes then every 10minutes till regression | 3.VAS: every 15 minutes in the first hour then hourly for 4 hours then at 12hours and 24 hours after spinal blockade
次要结局
- Sedation scale(Complications)