Lymph Node Ratio as a Predictor for Outcome in Rectal Cancer: a Retrospective Cohort
试验速览
- 阶段
- 不适用
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Lymph node value
研究概览
简要总结
This study aims to evaluate the value of the LNR as a prognostic indicator in patients with rectal cancer who offered total mesorectal excision.
详细描述
Patients and methods Study design and setting This is a retrospective review of prospectively collected and maintained database of patients with CRC admitted in the Oncology Center of Mansoura University (OCMU), the Colorectal Surgery Unit of Mansoura University Hospitals, and the Department of General Surgery of Alexandria University.
Selection criteria Patients of either gender aged 18 years or above who presented with rectal cancer of any stage will be included in the study. We will exclude patients with patients younger than 18 years; patients with synchronous colon cancer; synchronous liver, pulmonary or bones metastasis; or synchronous gastrointestinal cancer; or patients who were lost to follow-up.
Study endpoints The primary endpoint of the study is to assess the value of lymph node ratio (LNR) on the oncological outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •rectal cancer of TNM stage I-III
- •underwent radical resection with curative intent
排除标准
- •synchronous colon cancer
- •synchronous gastrointestinal cancer
- •underwent palliative resection
- •presented with intestinal obstruction
- •those lost to follow-up.
结局指标
主要结局
Lymph node value
时间窗: one year
Value in prediction of oncological outcomes
次要结局
未报告次要终点
研究者
Mostafa shalaby, MD, MSc, PhD
Lecturer of Colorectal Surgery
Mansoura University