NCT01175681已完成不适用
Effect of Remote Ischemia Preconditioning on Myocardial Injury in Patients Undergoing Heart Valve Surgery
Sun Yat-sen University1 个研究点 分布在 1 个国家目标入组 73 人开始时间: 2007年12月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 73
- 试验地点
- 1
- 主要终点
- plasma troponin I level
研究概览
简要总结
Remote ischaemic preconditioning has shown its cardiac protective effect during heart surgery including coronary artery bypass graft surgery, congenital heart disease and aneurysm. However, no data was reported on heart valve disease surgery. Rheumatic heart disease is one of the major heart diseases requiring surgery in China. Thus, the investigators chose heart valve disease as a focus to see whether remote ischaemic preconditioning also has cardiac protective effect during heart valve surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All heart valve diseases needing heart valve surgery.
排除标准
- •All four limbs existed ischemic condition
结局指标
主要结局
plasma troponin I level
时间窗: with 7 days after surgery
The investigators will measure the plasma troponin I level in several time points before and after surgery in each patient.
次要结局
- serum creatinine(within 7 days after surgery)
研究者
研究点 (1)
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