Study on the Effects of Unilateral Resistance Training on Lower Limb Muscle Strength and Symmetry After Anterior Cruciate Ligament Reconstruction Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- muscle strength
研究概览
简要总结
Brief Summary Study type: Randomized controlled trial (interventional). Purpose: To find out whether six weeks of unilateral resistance training (URT) improves lower-limb strength and inter-limb symmetry more than traditional bilateral resistance training (BRT) after anterior cruciate ligament reconstruction (ACLR).
Main questions:
Does URT produce better limb-symmetry in knee flexor/extensor peak torque than BRT? Does URT lead to larger gains in feed-forward motor control, Lysholm knee score and International Knee Documentation Committee 2000 (IKDC 2000) subjective rating? Comparison: Participants will be randomly assigned to URT (each exercise done one leg at a time) or BRT (both legs work together). Training volume, frequency, session length and progression rules are identical in both groups.
What participants will do: After giving consent, complete baseline tests of strength, motor control and knee questionnaires. Attend 3 supervised sessions per week for 6 weeks. Each session lasts ~70 min:
5 min warm-up on cycle ergometer 5 min core-stability work 50 min strength circuit (6 exercises, 2 min between sets, 3 min between exercises) 10 min stretching/cool-down One-repetition maximum (1RM) re-tested at week 3 to adjust load. Final assessment within 3 days after the last training session (same tests as baseline).
详细描述
Detailed Description This single-center, prospective, randomized controlled trial will enroll 48 patients who have undergone primary anterior cruciate ligament reconstruction (ACLR) at Chongli Campus, Peking University Third Hospital. After providing written informed consent, participants will be randomly allocated in a 1:1 ratio to either the unilateral resistance training (URT) group or the bilateral resistance training (BRT) group (24 per group).
URT: Each exercise is performed independently with one limb at a time, isolating the target limb while contralateral stabilizers are simultaneously activated to maintain balance.
BRT: Both limbs simultaneously move against a shared resistance, keeping the center of gravity stable and the movement symmetrical.
Baseline assessments will be completed within one week before the first training session; post-intervention testing will occur within three days after the final session. The program lasts six weeks, with three supervised sessions per week. Every session comprises:
5-min warm-up on a cycle ergometer 5-min core-stability work 50-min strength training (the only component that differs between groups) 10-min stretching and cool-down Six exercises are prescribed in identical order for both groups: towel-squeeze press, seated leg press, knee-extension against resistance, long-lever glute bridge, prone hamstring curl, and Romanian dead-lift. Two minutes of rest are given between sets; three minutes separate exercises. Load is set at 60 % of the relevant one-repetition maximum (1RM), re-tested at baseline and week 3 to allow progression.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 30-55 years
- •ACLR performed with hamstring-tendon autograft ≥ 3 months ago
- •Full extension (no loss) and ≤ 5° difference in knee-flexion range between limbs, with flexion ≥ 120°
- •Able to recruit quadriceps adequately (no lag during 10 consecutive straight-leg raises on the involved side)
- •Can stand pain-free on the involved leg for ≥ 5 s without support
- •Has signed informed consent and can complete all study procedures
排除标准
- •Previous lower-limb surgery on either leg, including revision ACLR
- •Any prior knee surgery on the contralateral limb
- •Associated ligament ruptures or fractures
- •Severe patellar chondral damage
- •Post-operative arthrofibrosis
- •Professional athletes
- •Cardiac disease
- •Pregnant or lactating women
结局指标
主要结局
muscle strength
时间窗: Baseline (1 day before the intervention) and 3 days after the final training session (day 45 of the study)
Isokinetic muscle strength test Before the test, the participants were instructed on the basic principles of isokinetic strength testing and were required to perform three maximum knee extensions as a warm-up. After the warm-up, the patients rested for 2 minutes, and then performed 5 repetitions at speeds of 60°/s and 180°/s. The peak torque values (PT) of the quadriceps and hamstring muscles of both limbs during the 5 attempts were recorded.
次要结局
- Thigh circumference measurement (unit: cm)(Baseline (1 day before the intervention) and 3 days after the final training session (day 45 of the study))
- Lysholm knee score scale(Baseline (1 day before the intervention) and 3 days after the final training session (day 45 of the study))
- Knee joint IKDC 2000 score(Baseline (1 day before the intervention) and 3 days after the final training session (day 45 of the study))
- Single-leg jump (unit: cm)(Baseline (1 day before the intervention) and 3 days after the final training session (day 45 of the study))
- Landing Error Scoring System,LESS(Baseline (1 day before the intervention) and 3 days after the final training session (day 45 of the study))