The Effects of Different Forms of Single Exercise Sessions on Cognitive Flexibility and Brain Functional Connectivity in Older Adults With Cognitive Impairment: A Single-Blind, Multicenter Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
研究概览
简要总结
Objectives: To investigate the effects of different forms (physical and mental, aerobic and resistance) of single exercise on the cognitive flexibility and brain functional connectivity of elderly individuals with cognitive impairment.
Clinical trail Methods: This study employed a single-blind, multi-center randomized controlled trial. Sixty elderly individuals with cognitive impairment were recruited and randomly divided into the Qigong group (15 participants), the brisk walking group (15 participants), the elastic band group (15 participants), and the control group (15 participants). Before and after the intervention, 5-minute resting-state electroencephalogram signals were collected and cognitive flexibility tests were conducted. The Qigong group, the brisk walking group, and the elastic band group received single sessions of Qigong, brisk walking, and elastic band exercises respectively, while the control group received health education. The exercise intensity was moderate (target heart rate was 64%-76% of the maximum heart rate), and the exercise duration was 30 minutes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 60 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 60 years old, gender not restricted;
- •Patients or their guardians report subjective cognitive decline;
- •Montreal Cognitive Function Assessment Scale < 26 points;
- •Duration of cognitive dysfunction ≥ 6 months;
- •Willing to sign the informed consent form;
- •Good physical condition and able to complete the test;
- •Right-handed.
排除标准
- •History of severe mental disorders (severe depression, schizophrenia, etc.);
- •Using drugs that affect cognition (such as sedatives, antidepressants, etc.);
- •Limited language ability;
- •Consumed caffeine or alcohol the day before the test;
- •Suffering from serious diseases or injuries that make participation in the test inappropriate.
研究者
Ding Feng
Principal Investigator
Shanghai University of Sport