NCT07579858已完成3 期
Efficacy of Platelet-rich Plasma on Blastocyst Formation in ICSI Cycles Involving Low-quality Sperm: A Randomised Study
Stella Maris Women and Children Hospital1 个研究点 分布在 1 个国家目标入组 66 人开始时间: 2023年1月1日最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 66
- 试验地点
- 1
研究概览
简要总结
The goal of this clinical trial is to learn if platelet rich plasma (PRP) works to improve embryo development rates and embryo quality in IVF cycles, involving male adult patients with severe sperm disorders.
The main questions it aims to answer are:
- Does PRP improve sperm quality of male adult patients undergoing IVF?
- Does PRP improve embryo development and embryo quality of the IVF patients?
Researchers will compare embryos from IVF patients treated with PRP to those not treated with PRP to see if PRP improves embryo development and embryo quality.
Participants will:
- Provide semen sample for IVF
- Provide blood sample for PRP preparation
- Have PRP obtained from their blood added to their sperm sample
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 28 Years 至 45 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •sperm concentration of less than five million/mL;
- •total sperm motility < 42%;
- •sperm normal morphology of less than four percent;
- •provided informed consent to participate in the study
排除标准
- •leukospermia;
- •a history of HIV, hepatitis, or other reproductive tract infections;
- •a history of utilising drugs or therapies within the past three months, such as antibiotics, radiotherapy, chemotherapy, psychiatric medications, or anabolic steroids;
- •a history of fever within the past three months;
- •a history of testicular carcinoma;
- •using a second ejaculate sample for ICSI;
- •using a cryopreserved semen sample for ICSI;
- •a history of retrograde ejaculation;
- •a history of coagulopathy
研究者
Binarwan Halim
Associate Professor
Stella Maris Women and Children Hospital
研究点 (1)
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