NL-OMON54415已完成不适用
Comparing the effect of a high SFA diet and high fructose diet on hepatic insulin sensitivity - SFA and fructose study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Participants are able to provide signed and dated written informed consent
- •prior to any study specific procedures
- •- Participants should have suitable veins for cannulation or repeated
- •venipuncture
- •- Women are post-menopausal (defined as at least 1 year post cessation of
- •- Aged >= 45 and <= 75 years
- •- Body mass index (BMI) 27 - 38 kg/m2
- •- Stable dietary habits (no weight loss or gain >5kg in the past 3 months)
- •- Sedentary lifestyle (not more than 2 hours of sports per week)
- •- No signs of active cardiovascular disease, liver or kidney malfunction
- •- Liver fat content >= 2% weight/weight.
排除标准
- •- Type 2 diabetes
- •- Previous enrolment in a clinical study with an investigational product during
- •the last 3 months or as judged by the Investigator
- •- Patients with congestive heart failure and and/or severe renal and or liver
- •insufficiency or another condition that may interfere with outcomes measured in
- •- Any contra-indication MRI scanning
- •- Alcohol consumption of >2 servings per day for men and >1 servings per day
- •- Smoking in the past 6 months
- •- Men: Hb <8.4 mmol/L, Women: Hb <7.8 mmol/l
- •- Vegetarian, vegan, food intolerant to common foods (e.g. gluten
- •intolerant, lactose intolerant)
- •- Medication use that may influence outcome parameters
- •A medical doctor will judge participation eligibility based on the medical
- •history questionnaire, medication use and fasting blood parameters. If the
- •medical doctor advises that a volunteer cannot participate, the volunteer will
- •be excluded from enrollment.
研究者
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