Anterior Segment Changes After Pars Plana Vitrectomy With Silicone Oil Tamponade And After Silicone Oil Evacuation Using AS-OCT.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Assessement of the changes in anterior chamber angle after vitrectomy with silicone oil injection
研究概览
简要总结
To evaluate changes in ACA induced by pars plana vitrectomy with SO 1000cs injection in vitreo-retinal surgery in phakic eyes using AS-OCT and changes in the IOP preoperatively, post-operatively and post-silicone oil evacuation.
详细描述
Abstract Introduction Ocular hypertension and secondary glaucoma are relatively common and serious complications in silicone filled eyes which may end in blindness. Reports have described the percentage of incidence to be within 3 - 30 % of silicon filled eye which are complicated with secondary glaucoma. [1] Aim of study Evaluation of changes in anterior chamber angle and intra-ocular pressure (IOP) in patients with rhegmatogenous retinal detachment (RRD) who underwent pars plana vitrectomy (PPV) with silicone oil (SO) 1000cs tamponade and after silicone oil evacuation.
Population The study was a prospective interventional study. The study included 30 eyes from 30 patients with rhegmatogenous retinal detachment (RRD) who are going to undergo PPV with SO injection. The study was conducted at Ophthalmology department, Minia University Hospital in Egypt between April 2023 and April 2024.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 16 Years 至 75 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •• Patients with rhegmatogenous retinal detachment who are going to undergo vitreoretinal surgery with silicone oil 1000cs injection as tamponade
排除标准
- •Patients with history of intraocular surgery, laser therapy or intravitreal injection.
- •Patients with significant corneal opacity.
- •Patients with ocular diseases as retinal vein occlusion, uveitis and proliferative diabetic retinopathy.
- •Patients with preexisting glaucoma or family history of glaucoma.
- •Patients with nystagmus.
- •Patient with tractional retinal detachment, exudative retinal detachment or intraocular foreign body.
- •Patients with anterior chamber abnormalities including posterior synechia, peripheral anterior synechia, hyphaema and iris abnormalities.
- •Patients with severe proliferative vitreoretinopathy grade C or more.
结局指标
主要结局
Assessement of the changes in anterior chamber angle after vitrectomy with silicone oil injection
时间窗: postoperative evaluation for 3 months duration (5 visits pre-ppv then one week, one month, three months )
Evaluation of changes in the anterior chamber angle parameters after vitrectomy with silicone oil 1000cs injection. The measures include AOD 500, TISA 500, ACA and CCT The measuring tool is AS-OCT (anterior segment optical coherent topography)
次要结局
未报告次要终点
研究者
Mohab Mohamed Khairy Talaat
Mohab Mohamed Khairy Talaat
Minia University