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临床试验/NL-OMON39664
NL-OMON39664招募中不适用

Thiazide diuretics versus calcium channel blockers for the treatment of tacrolimus-induced hypertension in dermatology patients: a single-center randomized cross-over trial. - TT-study

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 73 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
73

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • Treatment with tacrolimus
  • MDRD-GFR >= 30 ml/min
  • Systolic blood pressure > 140 mmHg but < 180 mmHg during 24-hours blood pressure measurement
  • Stable background antihypertensive drugs (i.e., no anticipated change in dose during the study period)
  • 18 years or older

排除标准

  • MDRD-GFR < 30 ml/min
  • Serum sodium < 136 mmol/l
  • Serum potassium < 3.5 mmol/l
  • Proteinuria > 1.0 g/10 mmol creatinine
  • Systolic blood pressure < 140 mmHg during 24-hour blood pressure measurement
  • The use of co-trimoxazol or prednisone
  • Incapacitated subjects
  • Pregnancy
  • Simultaneous use of thiazides and calcium channel blockers.
  • Use of loopdiuretics

研究者

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