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临床试验/NCT06855550
NCT06855550已完成不适用

Evaluation of Plasmatic Magnesium Levels and Its Association with Atrial Fibrillation After Cardiac Surgery

Fundación Cardioinfantil Instituto de Cardiología1 个研究点 分布在 1 个国家目标入组 435 人开始时间: 2015年5月4日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
435
试验地点
1
主要终点
Postoperative Atrial fibrilation

研究概览

简要总结

Introduction: Postoperative atrial fibrillation is one of the most frequent complications in cardiac surgery, with an expected incidence of more than 50% following valve surgery. Hypomagnesemia is also likely to be observed in the postoperative period, and several studies have suggested that it could be related to the incidence of postoperative atrial fibrillation. In this study, via a prospective design and adjustment for multiple covariates, the investigators will seek to determine whether plasma magnesium levels are independently associated with the appearance of postoperative atrial fibrillation.

Methods: An analytical design involving a concurrent cohort will be carried out in a high-complexity hospital with a cardiovascular focus. Serial postoperative plasma magnesium measurements will be included as independent variables in a logistic regression model to determine their association with atrial fibrillation after adjusting for multiple covariates.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Adults in postoperative cardiac surgery

排除标准

  • •Preoperative atrial fibrillation
  • •Without complete information regarding plasmatic magnesium postoperative measurements

结局指标

主要结局

Postoperative Atrial fibrilation

时间窗: Measurement was performed first day after surgery up to 30 days postoperatively or discharge (whichever came first)

Defined as irregular QRS without p wave during 30 seconds in a 12 derivations EKG.

次要结局

  • Mortality(Measurement was performed first day after surgery up to 30 days postoperatively or discharge (whichever came first))

研究者

发起方
Fundación Cardioinfantil Instituto de Cardiología
申办方类型
Other
责任方
Principal Investigator
主要研究者

Edgar Hernández Leiva

Head of Cardiovascular Critical Care

Fundación Cardioinfantil Instituto de Cardiología

研究点 (1)

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