NCT00980707已完成4 期
Utility of Versican and Hyaluronan Measurement in Induced Sputum as Biomarker of Asthma
Associated Scientists to Help Minimize Allergies1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2009年8月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Compare hyaluronan and versican in asthmatics versus atopic non-asthmatics.
研究概览
简要总结
The purpose of this study is to determine the role of versican and hyaluronan measurements in induced sputum as biomarkers of asthma. Enroll 10 subjects with mild persistent asthma who are not receiving treatment with a controller therapy.
详细描述
We will compare spirometry, eNO and sputum measurements of versican and hyaluronan before and after treatment with fluticasone 220 ug/bid.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Allergic asthma defined as a positive methacholine challenge
排除标准
- •Non-atopic patients
研究组 & 干预措施
inhaled corticosteroid
Experimental
All asthmatics will start inhaled corticosteroids.
干预措施: Inhaled corticosteroid (fluticasone) (Drug)
结局指标
主要结局
Compare hyaluronan and versican in asthmatics versus atopic non-asthmatics.
时间窗: 1 year
次要结局
未报告次要终点
研究者
研究点 (1)
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