The effect of spinal anaesthesia on ophthalmic artery doppler indices in severely pre eclamptic vs normotensive pregnant females undergoing caesarean section: A prospective observational case controlled study.

PGIMER Chandigarh0 个研究点目标入组 0 人开始时间: 待定最近更新: 2022年5月2日

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•1.Control group: 30 Normotensive (age and gestational age matched to cases) pregnant female planned for caesarean section under spinal anaesthesia
•2.Study group 2: Severely preeclamptic pregnant females who have received magnesium sulphate planned for caesarean section under spinal anaesthesia
•Criteria for severe pre-eclampsia 18
•Increased bloodpressure (BP; systolic BP is 140 mmHg or a diastolicBP is 90 mmHginawoman who was normotensiveprior to 20 weeks of gestation) accompanied byproteinuria(0.3 g protein in a 24-hour specimen) or increased BPaccompanied by one ormore severe complications of maternal end organ damage evenin the absence of proteinuria like
•1. Renal involvement with creatinine > 90 Âµmol/L
•2. Liver involvement with elevatedtransaminases and/or severe right upper quadrant or epigastric pain.
•3. Neurological complications like eclampsia, altered mental status, blindness, strokeor more commonly hyperreflexia whenaccompanied by clonus, severe heada-cheswhenaccompanied by hyperreflexia, and persistentvisual scotomata.
•4. Hematological complications (thrombocytopenia,disseminated intravascular coa-gulation or hemolysis)
•5. Uteroplacental dysfunction (fetal growth restriction)

•1.Patient Refusal
•2. Contraindications of spinal anesthesia
•3. Short stature <140 cm
•4. Allergy to any drugs used
•5. Chronic hypertension, Eclampsia
•6. Chronic renal disease, Hyperthyroidism, seizure disorder, noninsulin dependent di-abetes mellitus, severe anemia
•7. Twin gestation
•8. Autoimmune disorders
•9. Presence of ocular injuries or prior ocular surgery.

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