ITMCTR2100004335招募中1 期

Study on syndrome differentiation standard of yin deficiency syndrome in Alzheimer's disease

Traditional Chinese Pharmacological Laboratory, School of Traditional Chinese Medicine, Southern Medical University0 个研究点开始时间: 待定最近更新: 2023年2月20日

试验速览

暂无简介。

•(1) Aged 50-85 years;
•(2) According to the core clinical diagnostic criteria of Alzheimer's disease dementia (2011) of National Institute on aging and Alzheimer's Association (nia-aa) or mild cognitive impairment caused by Alzheimer's disease (2011); according to the diagnostic scale of yin deficiency syndrome of Alzheimer's disease, it was judged as yin deficiency syndrome; the course of memory loss was more than 6 months and confirmed by others The possible manifestations of AD (asymmetric atrophy of medial temporal lobe or hippocampus, etc.) were found on MRI scan;
•(3) Graduated from primary school or above, able to complete relevant tests and inspections;
•(4) The patients with mild and moderate condition: the total score of mini mental state examination >= 11 and < 27; the total score of clinical dementia rating scale >= 0.5 and <= 2; the total score of haginsky ischemia scale <= 4;
•(5) There are stable and reliable caregivers; voluntary and legal guardians agree to participate, and jointly sign the informed consent.

•(1) Dementia caused by other reasons;
•(2) severe cardiovascular system, respiratory system, digestive system, endocrine system, severe liver and kidney dysfunction;
•(3) Those who are definitely diagnosed with depression, anxiety and other mental diseases or are taking anti anxiety and depression drugs; take other traditional Chinese medicine containing experimental traditional Chinese medicine ingredients within one month;
•(4) Other situations that the researchers think are not suitable to participate in this study.

发起方

Traditional Chinese Pharmacological Laboratory, School of Traditional Chinese Medicine, Southern Medical University