DRKS00025989招募中不适用
Effect of medium-term, moderate hypoxia on sleep patterns, pulmonary blood flow, hemorheology, and exercise capacity in patients with Fontan circulation. - HYPOFO
Abteilung für Kinderkardiologie des Universitätsklinikums Bonn0 个研究点目标入组 20 人开始时间: 2022年1月5日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 16 Years 至 30 Years（—）
- 性别
- All
入选标准
- •Hemodynamically stable Fontan patients (10 w; 10 m).
- •- Age 16 to 30 years
- •- Peripheral saustoff saturation = 90%.
- •- Physical and mental ability to complete spiroergometry on a bicycle ergometer
- •- Signed informed consent (If underage, also signed informed consent from both parents).
排除标准
- •- Failing Fontan (protein-losing enteropathy, ascites, bronchitis plastica, NYHA stage III or IV).
- •- Fenestration in the Fontan tunnel
- •- Peripheral oxygen saturation < 90 % in normoxia
- •- Stent in pulmonary artery, Glenn anastomosis and/or proximal tunnel of Fontan
- •- Claustrophobia
- •- Obesity (BMI = 30)
- •- Cardiac pacemaker
- •- Acute infections
- •- Medication with sildenafil or bosentan
- •- Medication with hypnotics
- •- Known sleep disorders
- •- Known depression, previous psychiatric illnesses
研究者
相似试验
招募中
不适用
Mild intermittent hypoxia and metabolismObesity, Insulin resistance, Adipose tissue, Skeletal muscle, Inflammation, Metabolism(in dutch: Obesitas, Insulineresistentie, Vetweefsel, Skeletspier, Ontsteking, Stofwisseling)NL-OMON29164Maastricht University Medical Centre+12
已完成
不适用
Effects of moderate intermittent hypoxia exposure on peripheral insulin sensitivity and substrate metabolism in humansadult-onset diabetestype 2 diabetes mellitus10018424NL-OMON42717niversiteit Maastricht15
已完成
不适用
Autonomic Activity During Nap Under HypoxiaHypoxiaSleepHealthyNCT04146857Charite University, Berlin, Germany16
招募中
不适用
The study of the effects of nocturnal hypoxemia on the prognosis of respiratory diseasesRespiratory DiseasesJPRN-UMIN000017388Department of Occupational Health, Tohoku University Graduate School of Medicine760
已完成
不适用
Hepatic Drug Biotransformation in Children With Obstructive Sleep ApneaSleep ApneaNCT00310323Virginia Commonwealth University69