Superior Hypogastric Plexus Block for Early Recovery After Laparoscopic Colorectal Cancer Surgery: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 170
- 试验地点
- 1
研究概览
简要总结
This trial seeks to assess the efficacy of a superior hypogastric plexus block for early quality of recovery after laparoscopic colorectal cancer surgery.
详细描述
This study is a single-center, randomized, double-blind, placebo-controlled trial designed to evaluate the efficacy of superior hypogastric plexus block (SHPB) in improving the quality of postoperative recovery in patients undergoing laparoscopic colorectal cancer surgery. A total of 170 eligible patients will be enrolled and randomly assigned in a 1:1 ratio to receive either SHPB or placebo block. The primary outcome is the 15-item Quality of Recovery (QoR-15) score at 24 hours postoperatively. Secondary outcomes include visceral pain numerical rating scale (NRS) scores at rest and during movement within 48 hours postoperatively, morphine consumption, time to first flatus, incidence of postoperative ileus, length of hospital stay, and inflammatory cytokine levels (such as interleukin-6 and C-reactive protein). This study aims to elucidate the evidence-based medical position of SHP block within the Enhanced Recovery After Surgery (ERAS) strategy for laparoscopic colorectal cancer surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Able to provide informed consent.
- •Undergoing elective laparoscopic radical resection for colorectal cancer.
- •American Society of Anesthesiologists Physical Status (ASA) class I-III.
排除标准
- •Allergy to block medication (s).
- •Coagulation dysfunction.
- •Local or systemic infection.
- •Unable to cooperate with the completion of the study protocol.
研究者
Xiangcai Ruan, MD, PhD
Professor
Sixth Affiliated Hospital, Sun Yat-sen University
