Effect of Low-Level Laser Therapy Versus Hyaluronic Acid on Wound Healing After First Permanent Molar Extraction in Children.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- wound size
研究概览
简要总结
Tooth extraction may be an unpleasant and painful experience for children, Post-extraction wound healing. Low-level laser therapy (LLLT) is a widely used adjuvant treatment for wound healing, resulting in both an increase in cell number and an increase in cell metabolism. HA it is an important component of the extracellular matrix and a constituent of the neural, connective, and epithelial tissues.
详细描述
Tooth extraction may be an unpleasant and painful experience for children. Pain felt during dental treatment, especially tooth extraction, is the most common complication. Pain management during and after tooth extraction is part of behavioral guidance, especially in pediatric patients.
Post-extraction wound healing and pain perception are related to hostrelated factors such as the patient's immune system, the use of painkillers and antibiotics, the presence of infection in the region, and the atraumatic nature of the procedure. Low-level laser therapy (LLLT) is a widely used adjuvant treatment for wound healing. It is based on the idea that exposure to a specific wavelength can alter cellular behavior, resulting in both an increase in cell number and an increase in cell metabolism. Aside from not having any negative effects, LLLT is an a thermic, photobiological, and nondestructive therapy approach.
HA it is an important component of the extracellular matrix and a constituent of the neural, connective, and epithelial tissues. Among the many biological effects of HA are its functions in cell differentiation, wound healing, inflammation, embryological development, and viscoelasticity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
盲法说明
outcome assessors and statistician
入排标准
- 年龄范围
- 6 Years 至 10 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Children aged from six to ten years.
- •Children of both genders.
- •Children with badly decayed first permanent molar beyond repair and indicated for extraction.
- •Parents acceptance to participate in the study.
排除标准
- •Medically compromised children.
- •Uncooperative children.
- •Children who will not attend the follow up visits
研究组 & 干预措施
Low-Level Laser Therapy (LLLT)
Participants in this arm will receive low-level laser therapy (LLLT) immediately after extraction of the first permanent molar.
干预措施: Low-Level Laser Therapy (Device)
Hyaluronic Acid (HA)
Participants in this arm will receive hyaluronic acid (HA) immediately after extraction of the first permanent molar.
干预措施: Hyaluronic Acid (HA) (Drug)
结局指标
主要结局
wound size
时间窗: 7 days
Wound size unit of measure : mm (millimeters) (mesiodistal and buccolingual dimension of each socket).
次要结局
- Tissue Color Changes(Day 0, Day 3, and Day 7 post-extraction.)
- Bleeding Upon Palpation(Day 0, Day 3, and Day 7 post-extraction.)
- Pus Presence(Day 0, Day 3, and Day 7 post-extraction.)
- Pain Level During Application(Immediately after intervention (Day 0).)
研究者
Mona Ali Abd Elhafiz Ali
Bachelor Degree in Oral and Dental Medicine
Cairo University