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临床试验/NCT06571604
NCT06571604已完成不适用

Preoperative Gluteal Muscle Atrophy: A Silent Predictor of THA Dislocation.

Centre Hospitalier Universitaire de Nīmes1 个研究点 分布在 1 个国家目标入组 72 人开始时间: 2020年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
72
试验地点
1
主要终点
Mean Attenuation Ratio

研究概览

简要总结

This study looks at how fat buildup in hip muscles relates to hip osteoarthritis and less favorable recovery after hip replacement surgery. While it is known that weak gluteal muscles might cause problems, it is not yet proven if this specifically leads to hip dislocation after surgery. The goal of this study is to compare fat buildup in gluteal muscles between patients who had a hip dislocation soon after surgery and those who did not.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • primary THA with preoperative CT-scan

排除标准

  • malposition of acetabular implants outside the Lewinneck safe zone,
  • neurological or cognitive disorders,
  • associated spinal pathologies (within the context of a hip-spine syndrome),
  • chronic alcoholism,
  • aseptic osteonecrosis,
  • revision surgeries,
  • late dislocations attributed to polyethylene wear,
  • replacement following post-traumatic coxarthrosis due to acetabulum injuries.
  • diameters of the prosthetic heads ≠ 32mm

结局指标

主要结局

Mean Attenuation Ratio

时间窗: The CT scan of the pelvis used to plan the operation is performed between one and two months before the surgery.

The mean attenuation ratio (MAR), representing muscle fat degeneration, corresponds to the mean grayscale pixels in the selected area, expressed in Hounsfield Units (HU). Subsequently, the segmentation process was applied, selectively retaining pixels within the range of -30 HU to 150 HU. This range corresponds to muscle fibers and intramuscular fat, effectively excluding extra-fascial fat and bone pixels.

次要结局

  • Cross-Sectional Area(The CT scan of the pelvis used to plan the operation is performed between one and two months before the surgery.)
  • Intramuscular Fatty Fraction(The CT scan of the pelvis used to plan the operation is performed between one and two months before the surgery.)

研究者

发起方
Centre Hospitalier Universitaire de Nīmes
申办方类型
Other
责任方
Sponsor

研究点 (1)

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