Impact of SARS-CoV-2 Infection in a Population Aged 70 Years or Older on Loss of Autonomy
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 170
- 试验地点
- 5
- 主要终点
- Loss of autonomy
研究概览
简要总结
In most diseases, older people have less typical symptomatology than that described for younger people. The investigators therefore hypothesize that within the framework of coronavirus disease 19, the clinical pictures in the elderly will present specificities that will need to be described. Moreover, since infection by the severe acute respiratory syndrome (SARS-CoV-2) virus is new to humans, the investigators do not yet have sufficient information on the fate of the elderly, in terms of loss of autonomy, rehospitalization, institutionalization, mortality, etc. the investigators therefore assume that the clinical pictures in the elderly will present specificities that will need to be described. The investigators hypothesize that an acute infection of this type will have short-, medium-, and long-term repercussions in the elderly.
详细描述
The question of the outcome of elderly populations in the immediate aftermath of the epidemic and at a distance from it are essential to measure the effectiveness of the medical care that has been undertaken, but also to adapt the response to the specific problems of the elderly population. It is likely that the older, more fragile population will take longer to recover from the epidemic than the younger population because their functional reserves prior to coronavirus disease 19 are lower. In addition, the possible consequences of containment must be added to the burden of co-morbidities and dependence prior to the epidemic. Containment is synonymous with a restriction in social relationship, and sometimes a reduction in the support provided on a daily basis to frail or even dependent elderly people. Moreover, containment alone may be responsible for the onset or worsening of pathologies.
In most diseases, older people have less typical symptomatology than that described for younger people. The investigators therefore hypothesize that within the framework of coronavirus disease 19, the clinical pictures in the elderly will present specificities that will need to be described. Moreover, since infection by the SARS-CoV-2 virus is new to humans, the investigators do not yet have sufficient information on the fate of the elderly, in terms of loss of autonomy, rehospitalization, institutionalization, mortality, etc. The investigators therefore assume that the clinical pictures in the elderly will present specificities that will need to be described. The investigators hypothesize that an acute infection of this type will have short-, medium-, and long-term repercussions in the elderly.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 70 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •70 years of age or older;
- •Hospitalized in a short stay or a rehabilitation geriatric wards at one of the participating centers;
- •Positive by Reverse Transcriptase-Polymerase Chain Reaction for severe acute respiratory syndrome (SARS-CoV-2) coronavirus or be considered to have SARS-CoV-2 coronavirus based on lung CT data and physician opinion;
- •Formal consent to answer the questionnaire or, in the event of inability to give consent, consent obtained from the trusted third party;
- •Affiliation to a social security scheme.
排除标准
- •Patient under formal guardianship or trusteeship.
结局指标
主要结局
Loss of autonomy
时间窗: 36 months
Loss of autonomy (based on the variation of activity of daily living and instrumental activities of daily living score, and new formal or informal help)
次要结局
- All-cause mortality(Inclusion and 36 months)
- change in self-rated health(36 months)
- Hospital readmission(1 month follow-up)
- Nursing home admission(36 months)
