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临床试验/NCT02413112
NCT02413112已完成不适用

Minimum Resistance Training Frequency: Effect on Motivation and Adherence to Train, Overall Health Status and Neuromuscular Performance

University of Jyvaskyla0 个研究点目标入组 105 人开始时间: 2015年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
105
主要终点
Force production (Isometric and dynamic maximum strength tests of lower limbs)

研究概览

简要总结

It is well accepted that physical activity in the form of resistance training produces a wide variety of neuromuscular-skeletal and health benefits. It is recommended in Finland that older individuals (over 65yr) should perform resistance training twice per week.

Unfortunately, only approx. 5% of older individuals fulfill this recommendation. As Finnish society grows ever older, research should focus on the specific needs of this group and how to improve participation in physical activity, which may ultimately lead to modification of physical activity recommendations - resistance training recommendations are currently the same for young and older adults and do not include specific recommendations on the type of resistance training. However, these recommendations appear to have been developed for "best possible" improvements in maximum strength and muscle size.

Therefore, it is of great importance to identify the number of resistance training sessions per week required to induce improvements in physical fitness, metabolic and bone health status, and importantly the reasons for adherence to/drop-out of resistance training interventions (e.g. motivation to train) in a multi-discipline study. This knowledge would benefit policy makers to update current recommendations for resistance training and to devise strategies to advise realistic targets for resistance training in the older, particularly the less-educated, age group (e.g. TELI-strategy for 2020).

The present study will include a 12-month resistance training intervention with a 12-month follow-up period. Interviews and questionnaires will assess psychological/sociological data and will be collected from both drop-out subjects and those that complete the intervention. Neuromuscular performance and functional capacity will be tested using conventional methods, along with body composition, bone density, and blood tests for metabolic markers of health. Diet and other physical activity will be controlled throughout the intervention period. Measurements are to be performed every 3 months.

It is expected that 5 international peer-reviewed articles will be published in 2016-2017. The data will be presented at international and national conferences in 2015-2017. Finally, results of the entire research will be published in national peer-reviewed journals (e.g. The Age Institute's "Raportteja"). All subjects will be invited to attend an information meeting where group results will be presented and explained.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
65 Years 至 75 Years(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Does not smoke
  • Able to perform all tests and exercises
  • Free from episodes during physical activity

排除标准

  • Use of waling aids
  • Previous testosterone-altering treatment, e.g. in cancer treatment or hypogonadism
  • Serious cardiovascular disease that may lead to complications during exercise
  • Use of pharmaceuticals that affect neuromuscular or endocrine systems
  • Regular endurance training>3hr per week
  • Resistance training experience

结局指标

主要结局

Force production (Isometric and dynamic maximum strength tests of lower limbs)

时间窗: Change from baseline at 3, 9 and 15 months with data presented at 24 months post-initiation

Isometric and dynamic maximum strength tests of lower limbs

Muscle hypertrophy (Cross-sectional area of quadriceps and triceps surae muscles)

时间窗: Change from baseline at 3, 9 and 15 months with data presented at 24 months post-initiation

Cross-sectional area of quadriceps and triceps surae muscles

次要结局

  • Oral glucose tolerance test(Change from baseline at 3, 9 and 15 months with data presented at 24 months post-initiation)
  • Blood count(Change from baseline at 3, 9 and 15 months with data presented at 24 months post-initiation)
  • Basal hormone concentrations(Change from baseline at 3, 9 and 15 months with data presented at 24 months post-initiation)
  • Body composition (DXA scanning)(Change from baseline at 3, 9 and 15 months with data presented at 24 months post-initiation)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Simon Walker

Post-doctoral researcher

University of Jyvaskyla

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